Evaluation of the Effectiveness of a Web-based Treatment Program for Depression for the Reduction of Depressive Symptoms
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|ClinicalTrials.gov Identifier: NCT01401296|
Recruitment Status : Completed
First Posted : July 25, 2011
Last Update Posted : December 12, 2014
200 persons with depression are recruited via internet depression forums devoted to depression and are randomly assigned either to the online program deprexis or to a wait-list control condition. All participants receive free-of-charge online access to deprexis either immediately or with an eight week delay.
Prior to intervention and eight weeks later, both groups are assessed via an anonymous online survey which was implemented using the software package OPST®. The survey consists of different questionnaires. The Beck Depression Inventory (BDI) represents the primary outcome. It is assumed that the severity of depressive symptoms will improve to a significantly greater extent in the deprexis than in the wait-list control condition in the course of eight weeks.
|Condition or disease||Intervention/treatment||Phase|
|Depression||Behavioral: Deprexis Behavioral: Wait-list||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||200 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Single (Outcomes Assessor)|
|Official Title:||Evaluation of the Effectiveness of a Web-based Treatment Program for Depression (Deprexis) for the Reduction of Depressive Symptoms. A Randomized Controlled Trial|
|Study Start Date :||May 2011|
|Actual Primary Completion Date :||September 2012|
|Actual Study Completion Date :||September 2012|
Active Comparator: Wait-list group
Subjects receive access to deprexis after eight weeks
Behavioral: the wait-list group receives Deprexis after 8 weeks
Other Name: web-based treatment for depression after 8 weeks
Web-based intervention deprexis consists of ten online modules (plus one introductory and one summary module) representing different psychotherapeutic strategies with a strong focus on evidence-based cognitive-behavioral techniques (e.g. interpersonal skills). Each module lasts approximately 10-60 minutes (e.g. depending on the user´s reading speed). Modules are sequential and organized as simulated dialogues. Each module refers and builds upon previous one. The program is delivered at no cost to participants.
Behavioral: Deprexis (10 sessions) delivered online versus wait-list control group
Other Name: web-based treatment program for depression
- Severity of depressive symptoms [ Time Frame: 7 Days ]Severity of depressive symptoms as assessed with the Beck Depression Inventory (BDI)
- quality of life as assessed by the WHO Quality of Life scale (WHO-QOL BREF) [ Time Frame: 7 days ]The WHO-QOL- Bref is an abbreviated 26-item version of the WHO-QOL-100 which covers four domains of quality of life (QoL): physical. psychological. social. environment.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01401296
|University Medical Center Hamburg-Eppendorf|
|Hamburg, Germany, 20246|
|Principal Investigator:||Steffen Mortz, PhD||Universitätsklinikum Hamburg-Eppendorf|