Diagnostic Performances of Computed TomographIc Coronary Angiography and Intravascular Ultrasound (IMAGES-FFR)
|ClinicalTrials.gov Identifier: NCT01400230|
Recruitment Status : Completed
First Posted : July 22, 2011
Last Update Posted : March 24, 2015
|Condition or disease||Intervention/treatment|
|Diagnosis Coronary Artery Disease||Procedure: diagnostic procedures CCTA, CAG, IVUS and FFR|
Correlation between CCTA, IVUS and FFR will be evaluated. The presence of myocardial ischemia will be assessed by fractional flow reserve (FFR).
Diagnostic performance (sensitivity, specificity, positive predictive/negative predictive values and diagnostic accuracy) of each modality will be assessed and compared.
|Study Type :||Observational|
|Actual Enrollment :||150 participants|
|Official Title:||Diagnostic Performances of the Computed Tomographic Coronary Angiography and IntraVascular UltraSound to Evaluate Ischemia Causing Coronary Artery Stenosis|
|Study Start Date :||March 2008|
|Primary Completion Date :||December 2011|
|Study Completion Date :||December 2011|
Patients suspected ischemic heart disease by the symptom and CCTA and undergone IVUS and FFR in the Cath Lab with CAG enrolled consecutively.
Procedure: diagnostic procedures CCTA, CAG, IVUS and FFR
Diagnostic procedures including computed tomography, coronary angiography, intravascular ultrasound, fractional flow reserve were performed in the patients suspected ischemic heart disease.
- Diagnostic accuracy [ Time Frame: 1 day ]
Evaluate and compare the diagnostic accuracy of the CCTA, IVUS and angiographic parameters for the prediction of myocardial ischemia (FFR<0.8)
- CCTA: % area stenosis
- IVUS: minimum lumen area
- Angiography: % diameter stenosis
Diagnostic accuracy of each parameter: (true positive+true negative)/total cases
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01400230
|Korea, Republic of|
|Inje University Ilsan Paik Hospital|
|Goyang, Gyeonggi-do, Korea, Republic of, 411-706|
|Study Director:||Joon Hyung Doh, MD, PhD||Inje University|
|Principal Investigator:||Bon-Kwon Koo, MD, PhD||Seoul National University Hospital|