International Multicenter Registry for Mechanical Recanalization Procedures in Acute Stroke (ENDOSTROKE)
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ClinicalTrials.gov Identifier: NCT01399762 |
Recruitment Status
: Unknown
Verified July 2011 by Goethe University.
Recruitment status was: Recruiting
First Posted
: July 22, 2011
Last Update Posted
: July 22, 2011
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Condition or disease | Intervention/treatment |
---|---|
Acute Stroke | Device: mechanical recanalization |
Study Type : | Observational |
Estimated Enrollment : | 500 participants |
Observational Model: | Cohort |
Official Title: | International Multicenter Registry for Mechanical Recanalization Procedures in Acute Stroke (ENDOSTROKE) |
Study Start Date : | January 2011 |
Group/Cohort | Intervention/treatment |
---|---|
mechanical recanalization
Patients with acute stroke being treated with endovascular devices for mechanical recanalization (no restriction to specific endovascular devices)
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Device: mechanical recanalization
Endovascular thrombus extraction by mechanical recanalization devices
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- Clinical outcome [ Time Frame: approx. 90 days after stroke onset ]Proportion of patients with favourable clinical outcome defined as a Modified Rankin Score (MRS) of 0,1, or 2 three months after the intervention.
- Angiographic outcome [ Time Frame: Day of intervention ]Proportion of patients with complete recanalization defined as Thrombolysis in Myocardial Infarction (TIMI) Grade 2 or 3.
- Complication rate [ Time Frame: within 36 h after endovascular procedure ]Periprocedural complication rate defined as a combination of symptomatic intracranial hemorrhage (ECASS classification PH I and PH II), subarachnoid hemorrhage and thrombembolic events.

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Ages Eligible for Study: | 18 Years and older (Adult, Senior) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Sampling Method: | Non-Probability Sample |
Inclusion Criteria:
- Patients being treated with mechanical recanalization devices due to an acute proximal arterial vessel occlusion of brain supplying arteries
Exclusion Criteria:
- Patients being treated with mechanical recanalization devices for venous vessel occlusion.
- Patients being treated with mechanical recanalization devices due to an acute vessel occlusion which occured as a complication of an angiographic procedure scheduled for other reasons (i.e. as a complication of a diagnostic angiography or coiling procedure for cerebral aneurysms)

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01399762
Contact: Oliver C Singer, MD | +49 69 6301 5942 | o.singer@em.uni-frankfurt.de | |
Contact: Joachim Berkefeld, MD | +49 69 6301 5462 | berkefeld@em.uni-frankfurt.de |
Austria | |
Departments of Neurology and Neuroradiology, University Hospital | Recruiting |
Graz, Austria, 8036 | |
Departments of Neurology and Neuroradiology, Landes-Nervenklinik Wagner-Jauregg | Recruiting |
Linz, Austria, 4020 | |
Germany | |
Departments of Neurology and Neuroradiology, University Hospital | Active, not recruiting |
Aachen, Germany, 52074 | |
Departments of Neurology and Radiology, Klinikum Altenburger Land | Not yet recruiting |
Altenburg, Germany, 04600 | |
Departments of Neurology and Neuroradiology, Charite University Hospital | Recruiting |
Berlin, Germany, 10117 | |
Departments of Neurology and Neuroradiology, University Hospital | Active, not recruiting |
Duesseldorf, Germany, 40255 | |
Departments of Neurology and Neuroradiology, University Hospital | Recruiting |
Essen, Germany, 45122 | |
Hirngefaesszentrum Goethe University | Recruiting |
Frankfurt, Germany, 60528 | |
Departments of Neurology and Neuroradiology, Klinikum Fulda | Recruiting |
Fulda, Germany, 36043 | |
Departments of Neurology and Neuroradiology, University Hospital | Active, not recruiting |
Giessen, Germany, 35385 | |
Departments of Neurology and Neuroradiology, University Hospital | Active, not recruiting |
Kiel, Germany, 24105 | |
Departments of Neurology and Neuroradiology, University Hospital | Active, not recruiting |
Mainz, Germany, 55131 | |
Departments of Neurology and Neuroradiology, Knappschaftskrankenhaus | Active, not recruiting |
Recklinghausen, Germany, 45657 |
Principal Investigator: | Oliver C. Singer, MD | Hirngefaesszentrum Goethe University Frankfurt Germany | |
Principal Investigator: | Joachim Berkefeld, MD | Hirngefaesszentrum Goethe University Frankfurt Germany |
Responsible Party: | PD Dr. med. Oliver C. Singer, Hirngefaesszentrum der Goethe Universitaet |
ClinicalTrials.gov Identifier: | NCT01399762 History of Changes |
Other Study ID Numbers: |
Endostroke_01 |
First Posted: | July 22, 2011 Key Record Dates |
Last Update Posted: | July 22, 2011 |
Last Verified: | July 2011 |
Keywords provided by Goethe University:
stroke, acute mechanical recanalization interventional neuroradiology clinical registry |
Additional relevant MeSH terms:
Stroke Cerebrovascular Disorders Brain Diseases Central Nervous System Diseases |
Nervous System Diseases Vascular Diseases Cardiovascular Diseases |