Cranberry Enhances Human Immune Function and Reduces Illness
![]() |
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
ClinicalTrials.gov Identifier: NCT01398150 |
Recruitment Status :
Completed
First Posted : July 20, 2011
Last Update Posted : September 20, 2011
|
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
Condition or disease | Intervention/treatment | Phase |
---|---|---|
Healthy Humans | Dietary Supplement: Beverage made to look like the cranberry beverage Dietary Supplement: Beverage made from cranberry compounds | Not Applicable |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 54 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor) |
Primary Purpose: | Basic Science |
Official Title: | Cranberry Enhances Human Immune Function and Reduces Illness |
Study Start Date : | March 2009 |
Actual Primary Completion Date : | May 2009 |
Actual Study Completion Date : | May 2009 |
Arm | Intervention/treatment |
---|---|
Placebo Comparator: Sweetened Beverage
looks like and is given in the same way as the experimental treatment but contains no active ingredient
|
Dietary Supplement: Beverage made to look like the cranberry beverage
one 15 ounce bottle of beverage consumed daily |
Experimental: Cranberry Beverage
15 ounce bottle of cranberry beverage consumed daily for 70 days
|
Dietary Supplement: Beverage made from cranberry compounds
one 15 ounce bottle consumed daily for 70 days |
- Physiological modifications to immune cell function [ Time Frame: 70 days ]Proliferation of γδ-T cells when cultured ex vivo in autologous serum
- Cold and flu symptoms [ Time Frame: 70 days ]Incidence and severity of cold and flu symptoms, total and individual. Other signs of severity, for example, visits to doctor or health clinic, reduction in daily activities, medications prescribed or purchased OTC.
- Anti-inflammatory outcome [ Time Frame: 70 days ]Serum antioxidant status, cytokine production and proliferation of αβ-T, B and NK cells

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study: | 18 Years to 50 Years (Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
- Health male or non-pregnant female
- Between the ages of 21 and 50
- BMI between 18 and 35
Exclusion Criteria:
- High blood pressure define as 140/90
- Ongoing or chronic illness or infection
- On hypertensive medication, immunosuppressive drugs, antibiotics, or chronic use of NSAIDS
- Taking plant-based dietary supplements, antioxidant supplements, or probiotics
- Vegetarian or strict vegan
- Consume more than 1 cup of tea (iced or hot) per day
- Consumes more than 2 glasses of alcoholic beverages per day
- Consume more than 7 fruits and vegetables per day

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01398150
United States, Florida | |
449 Food Science and Human Nutrition Department | |
Gainesville, Florida, United States, 32611 |
Principal Investigator: | Susan S Percival, PhD | University of Florida |
Responsible Party: | University of Florida |
ClinicalTrials.gov Identifier: | NCT01398150 |
Other Study ID Numbers: |
CB-79545 |
First Posted: | July 20, 2011 Key Record Dates |
Last Update Posted: | September 20, 2011 |
Last Verified: | February 2010 |
gamma delta T cell proliferation cytokine secretion immune function antioxidant status |