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Respiratory Quotient in Post Roux-en-Y Gastric Bypass Patients (RQ)

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01396460
First Posted: July 18, 2011
Last Update Posted: September 10, 2012
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Silvia Leite Faria, Gastrocirurgia, Brazil
  Purpose

Through the values of respiratory quotient (RQ) it is possible to estimate the utilization of energy substrates by the body, or if there is a higher or lower fat oxidation. Experimental and clinical studies have shown that after Roux-en-Y Gastric Bypass (RYGBP) there is a decrease in the values of RQ, which may be associated with increased lipid oxidation in the postoperative period.

Diet Induced Thermogenesis (DIT) is an important part of Total Energy Expenditure. We would like to know how it functions among RYGBP patients.

The purpose of this study is to evaluate the RQ and DIT of patients in the post operative phase and compare the result with a control group consisting of morbid obese population.


Condition Intervention
Morbid Obesity Other: breakfast (a chicken sandwich with juice)

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Cross-Sectional
Official Title: Respiratory Quotient in Post Roux-en-Y Gastric Bypass Patients

Further study details as provided by Silvia Leite Faria, Gastrocirurgia, Brazil:

Primary Outcome Measures:
  • Diet Induced Thermogenesis [ Time Frame: 20min after standard meal ]
    To examine the possible changes in the thermic effect of food, the patients received a standard meal. They then repeated the test 20 minutes after eating to obtain a reading of the metabolic rate by considering the DIT and RQ in the postprandial period. DIT was calculated as the difference between post prandial metabolic rate and RMR.


Enrollment: 69
Study Start Date: May 2011
Study Completion Date: July 2011
Primary Completion Date: June 2011 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
bariatric patients
Bariatric post operative patients were compared with morbid obese population
Other: breakfast (a chicken sandwich with juice)
patients received a breakfast after de initial measurement
control group
morbid obese population

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   20 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Bariatric post operative population
Criteria

Inclusion Criteria (bariatric patients post-op)

  • With more than 1 year after surgery
  • Consent given to participate

Exclusion Criteria:

  • Pregnant women
  • Malnourished patients (anemia)
  • Tiroid disorders without treatment
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01396460


Locations
Brazil
Gastrocirurgia de Brasilia
Brasilia, Distrito Federal, Brazil, 70390108
Sponsors and Collaborators
Gastrocirurgia, Brazil
  More Information

Responsible Party: Silvia Leite Faria, Silvia Leite Faria , MSc, RD, Gastrocirurgia, Brazil
ClinicalTrials.gov Identifier: NCT01396460     History of Changes
First Submitted: July 15, 2011
First Posted: July 18, 2011
Last Update Posted: September 10, 2012
Last Verified: September 2012

Keywords provided by Silvia Leite Faria, Gastrocirurgia, Brazil:
respiratory quotient
fat oxidation
morbid obesity
bariatric
Bariatric Surgery

Additional relevant MeSH terms:
Obesity, Morbid
Obesity
Overnutrition
Nutrition Disorders
Overweight
Body Weight
Signs and Symptoms