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Can Computer-based Telephone Counseling Improve Long-term Adherence to Strength Training in Elders With Knee OA? (BOOST)

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified May 2013 by Kristin Baker, PhD, Boston University.
Recruitment status was:  Recruiting
U.S. Department of Education
Information provided by (Responsible Party):
Kristin Baker, PhD, Boston University Identifier:
First received: June 21, 2011
Last updated: May 1, 2013
Last verified: May 2013
The purpose of this intervention is to determine whether computer-based telephone counseling will improve adherence to strength training in a population of elders with knee osteoarthritis.

Condition Intervention
Osteoarthritis of the Knee Behavioral: TLC

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Investigator)
Primary Purpose: Treatment
Official Title: Can Computer-based Telephone Counseling Improve Long-term Adherence to Strength Training in Elders With Knee OA?

Resource links provided by NLM:

Further study details as provided by Kristin Baker, PhD, Boston University:

Primary Outcome Measures:
  • Exercise Adherence [ Time Frame: Average adherence over the 24 month follow-up period. ]
    In the literature, adherence is assessed on a continuum as the number of sessions of exercises reported divided by prescribed. This does not provide information on how consistent a participant was in doing exercise and consistency of strength training is critical to its effectiveness. We developed a measure of adherence that reflects consistency, choosing a threshold of a minimum of 1 time per week for 80% of the weeks. An 80% threshold permits vacations/illness/life events that may limit exercise opportunities. We will also measure adherence by exercise sessions performed/sessions prescribed.

Secondary Outcome Measures:
  • Instruments [ Time Frame: Change in self-report pain and function from baseline to the 24 month interval. ]
    The Western Ontario/McMaster Universities Osteoarthritis Index (WOMAC), National Institutes of Health, Patient Reported Outcomes Measurement Information System (NIH PROMIS) for physical function, and the Osteoarthritis computer adaptive test methodology (OA-CAT) instrument will be assessed at baseline, post the 1-month exercise class, at the 12 and 24 month follow-up clinic visits and by telephone at 6 and 18 months. We will examine the association of adherence, as a dichotomous and continuous variable, to change in pain and function on these instruments.

  • Quadriceps strength [ Time Frame: Change in quadriceps strength from baseline to 24 months. ]
    Isokinetic quadriceps strength will be assessed with a Biodex at baseline, post the 1-month exercise class and at the 12 and 24 month follow-up clinic visits. The association of adherence as a dichotomous and continuous variable to change in quadriceps strength will be assessed.

  • Timed Physical Function tasks [ Time Frame: Change in timed physical function task over 24 months ]
    Timed physical function tasks will include a timed get up and go, timed stair ascent and descent, and a 5 and 10 chair stand time. We will examine the association of adherence, as a dichotomous and continuous variable, to change in timed physical function using logistic and linear regression, respectively.

  • Exercise quality [ Time Frame: Average measure of exercise quality over 24 months ]
    The outcome will be assessed at the end of the 24 month follow-up period as the number of calendar periods (1 month per calendar period) that the participant exercises at least half the number of prescribed sessions (a minimum of 6 out of 12 over a 4 week period) with the agreed upon level of intensity.

Estimated Enrollment: 100
Study Start Date: July 2011
Estimated Study Completion Date: September 2015
Estimated Primary Completion Date: September 2015 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Telephone-linked Communication (TLC)
This group will receive the computer-based telephone counseling.
Behavioral: TLC
Computer-based telephone linked communication will be used to counsel subjects to adhere to their exercise program over time.
No Intervention: Control
This is the control group. They will receive the exercise class, however, they will not receive the telephone counseling.


Ages Eligible for Study:   55 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • osteoarthritis of the knee (ICD-9 Code of 715.16, 715.09 or 715.9)
  • lives within interstate 95
  • age 55 or older
  • English speaking

Exclusion Criteria:

  • Stroke or MI in last 3 months
  • Treatment for cancer
  • Severe systemic disease
  • Medical condition that limits p.a.
  • Inflammatory arthritis
  • Plans for knee replacement
  • Dementia or inability to follow exercise instructions and TLC system
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01394874

Contact: Kristin R Baker, PhD 617-358-1637

United States, Massachusetts
Boston University Recruiting
Boston, Massachusetts, United States, 02215
Contact: Kristin Baker, PhD    617-358-1637   
Sponsors and Collaborators
Boston University
U.S. Department of Education
Principal Investigator: Kristin Baker, PhD Boston University
  More Information

Additional Information:
Responsible Party: Kristin Baker, PhD, Research Assistant Professor, Boston University Identifier: NCT01394874     History of Changes
Other Study ID Numbers: H133B100003-2
Study First Received: June 21, 2011
Last Updated: May 1, 2013

Keywords provided by Kristin Baker, PhD, Boston University:

Additional relevant MeSH terms:
Osteoarthritis, Knee
Joint Diseases
Musculoskeletal Diseases
Rheumatic Diseases processed this record on September 25, 2017