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Analgesic Effects of Intravenous Paracetamol on Labor Pain

This study has been completed.
King Abdulaziz Medical City
Information provided by:
King Abdulaziz University Identifier:
First received: July 12, 2011
Last updated: July 13, 2011
Last verified: July 2011
The purpose of this study is to determine whether intravenous paracetamol is effective in treating labor pain.

Condition Intervention Phase
Labor Pain Drug: Acetaminophen Drug: Meperidine Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Analgesic Effects of Intravenous Acetaminophen on Labor Pain

Resource links provided by NLM:

Further study details as provided by King Abdulaziz University:

Primary Outcome Measures:
  • Visual analogue scale (VAS) score for pain [ Time Frame: Up to 24 hours ]
    Patients who give written informed consent to participate will be entered into the study. Their VAS score will be determined every hour from the time of randomization until delivery of the baby. This time will vary from one patient to another depending on the duration of labor.

Study Start Date: December 2010
Study Completion Date: July 2011
Primary Completion Date: July 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Paracetamol 1 Drug: Acetaminophen
Experimental: Paraceatmol 2 Drug: Acetaminophen
Active Comparator: Meperidine Drug: Meperidine


Ages Eligible for Study:   18 Years to 60 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • American Society of Anesthesiologists physical class I-II
  • term patients (≥ 37 weeks of gestation)

Exclusion Criteria:

  • previous cesarean section
  • hypertension, pre-eclampsia, eclampsia
  • intra-uterine growth retardation
  • intrauterine fetal death
  • morbid obesity (body mass index ≥ 35)
  • allergy to any of the study drugs
  Contacts and Locations
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Please refer to this study by its identifier: NCT01394731

Saudi Arabia
King Abdulaziz Medical City
Riyadh, Central, Saudi Arabia, 11426
Sponsors and Collaborators
King Abdulaziz University
King Abdulaziz Medical City
  More Information

Responsible Party: Prof. Jamal A. Alhashemi, King Abdulaziz University Identifier: NCT01394731     History of Changes
Other Study ID Numbers: RC08-052
Study First Received: July 12, 2011
Last Updated: July 13, 2011

Additional relevant MeSH terms:
Labor Pain
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms
Analgesics, Non-Narcotic
Sensory System Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
Analgesics, Opioid
Central Nervous System Depressants
Adjuvants, Anesthesia processed this record on August 18, 2017