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Cognitive Training in Parkinson's Disease

This study has been completed.
Information provided by (Responsible Party):
University Hospital, Basel, Switzerland Identifier:
First received: July 6, 2011
Last updated: December 12, 2014
Last verified: December 2014
The study evaluates a computerized cognitive therapy in patients with Parkinson's disease who have a mild cognitive impairment or mild dementia. The control group is "trained" using Nintendo Wii. The main outcome parameter is a neuropsychological evaluation.

Condition Intervention
Mental Competence Other: Cognitive Training Other: computer game

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Participant)
Primary Purpose: Treatment
Official Title: A Computerized, Multidimensional and Disease Specific Training of Cognition in Patients With M. Parkinson

Resource links provided by NLM:

Further study details as provided by University Hospital, Basel, Switzerland:

Primary Outcome Measures:
  • Neuropsychological parameters: Tests of episodic memory, working memory, executive functions, visio-construction [ Time Frame: Neuropsychological assessment immediatly before and after the training and 6 month later ]
    Neuropsychological tests: mini mental status (MMS), Clock drawing test, Boston Naming Test, Calculating, Semantic Fluency, Phonematic Fluency, California Verbal Learning Test, Corsi Block Tapping Test, Trail Making Test, Digit Span, Testbatterie zur Aufmerksamkeitsprüfung (alteredness, Working Memory, Divided Attention, Flexibility), Wisconsin Card Sorting Test, Apraxias, 5 Points Test, Mosaik Test

Enrollment: 39
Study Start Date: May 2011
Study Completion Date: April 2014
Primary Completion Date: April 2014 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Sham Comparator: Computer game
Nintendo Wii
Other: computer game
Experimental: Cognitive Training with Cogniplus
Other: Cognitive Training


Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Parkinson's disease and mild cognitive impairment (MCI) or mild dementia

Exclusion Criteria:

  • Moderate or severe dementia, other pathologies of the brain, physical conditions that prevent the participation, unsufficient knowledge of german, pregnancy
  Contacts and Locations
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Please refer to this study by its identifier: NCT01393353

University Hospital Basel
Basel, Switzerland, 4031
Sponsors and Collaborators
University Hospital, Basel, Switzerland
Principal Investigator: Peter Fuhr, Prof. University Hospital Basel, Neurology
  More Information

Responsible Party: University Hospital, Basel, Switzerland Identifier: NCT01393353     History of Changes
Other Study ID Numbers: UHBS
Study First Received: July 6, 2011
Last Updated: December 12, 2014 processed this record on September 21, 2017