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Cognitive Training in Parkinson's Disease

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT01393353
Recruitment Status : Completed
First Posted : July 13, 2011
Last Update Posted : December 15, 2014
Sponsor:
Information provided by (Responsible Party):

Study Description
Brief Summary:
The study evaluates a computerized cognitive therapy in patients with Parkinson's disease who have a mild cognitive impairment or mild dementia. The control group is "trained" using Nintendo Wii. The main outcome parameter is a neuropsychological evaluation.

Condition or disease Intervention/treatment
Mental Competence Other: Cognitive Training Other: computer game

Study Design

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 39 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Participant)
Primary Purpose: Treatment
Official Title: A Computerized, Multidimensional and Disease Specific Training of Cognition in Patients With M. Parkinson
Study Start Date : May 2011
Primary Completion Date : April 2014
Study Completion Date : April 2014

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Arms and Interventions

Arm Intervention/treatment
Sham Comparator: Computer game
Nintendo Wii
Other: computer game
Experimental: Cognitive Training with Cogniplus
CogniPlus
Other: Cognitive Training


Outcome Measures

Primary Outcome Measures :
  1. Neuropsychological parameters: Tests of episodic memory, working memory, executive functions, visio-construction [ Time Frame: Neuropsychological assessment immediatly before and after the training and 6 month later ]
    Neuropsychological tests: mini mental status (MMS), Clock drawing test, Boston Naming Test, Calculating, Semantic Fluency, Phonematic Fluency, California Verbal Learning Test, Corsi Block Tapping Test, Trail Making Test, Digit Span, Testbatterie zur Aufmerksamkeitsprüfung (alteredness, Working Memory, Divided Attention, Flexibility), Wisconsin Card Sorting Test, Apraxias, 5 Points Test, Mosaik Test


Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Parkinson's disease and mild cognitive impairment (MCI) or mild dementia

Exclusion Criteria:

  • Moderate or severe dementia, other pathologies of the brain, physical conditions that prevent the participation, unsufficient knowledge of german, pregnancy
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01393353


Locations
Switzerland
University Hospital Basel
Basel, Switzerland, 4031
Sponsors and Collaborators
University Hospital, Basel, Switzerland
Investigators
Principal Investigator: Peter Fuhr, Prof. University Hospital Basel, Neurology
More Information

Responsible Party: University Hospital, Basel, Switzerland
ClinicalTrials.gov Identifier: NCT01393353     History of Changes
Other Study ID Numbers: UHBS
First Posted: July 13, 2011    Key Record Dates
Last Update Posted: December 15, 2014
Last Verified: December 2014