Cognitive Training in Parkinson's Disease

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
University Hospital, Basel, Switzerland
ClinicalTrials.gov Identifier:
NCT01393353
First received: July 6, 2011
Last updated: December 12, 2014
Last verified: December 2014
  Purpose

The study evaluates a computerized cognitive therapy in patients with Parkinson's disease who have a mild cognitive impairment or mild dementia. The control group is "trained" using Nintendo Wii. The main outcome parameter is a neuropsychological evaluation.


Condition Intervention
Mental Competence
Other: Cognitive Training
Other: computer game

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single Blind (Subject)
Primary Purpose: Treatment
Official Title: A Computerized, Multidimensional and Disease Specific Training of Cognition in Patients With M. Parkinson

Resource links provided by NLM:


Further study details as provided by University Hospital, Basel, Switzerland:

Primary Outcome Measures:
  • Neuropsychological parameters: Tests of episodic memory, working memory, executive functions, visio-construction [ Time Frame: Neuropsychological assessment immediatly before and after the training and 6 month later ] [ Designated as safety issue: No ]
    Neuropsychological tests: mini mental status (MMS), Clock drawing test, Boston Naming Test, Calculating, Semantic Fluency, Phonematic Fluency, California Verbal Learning Test, Corsi Block Tapping Test, Trail Making Test, Digit Span, Testbatterie zur Aufmerksamkeitsprüfung (alteredness, Working Memory, Divided Attention, Flexibility), Wisconsin Card Sorting Test, Apraxias, 5 Points Test, Mosaik Test


Enrollment: 39
Study Start Date: May 2011
Study Completion Date: April 2014
Primary Completion Date: April 2014 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Sham Comparator: Computer game
Nintendo Wii
Other: computer game
Experimental: Cognitive Training with Cogniplus
CogniPlus
Other: Cognitive Training

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Parkinson's disease and mild cognitive impairment (MCI) or mild dementia

Exclusion Criteria:

  • Moderate or severe dementia, other pathologies of the brain, physical conditions that prevent the participation, unsufficient knowledge of german, pregnancy
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01393353

Locations
Switzerland
University Hospital Basel
Basel, Switzerland, 4031
Sponsors and Collaborators
University Hospital, Basel, Switzerland
Investigators
Principal Investigator: Peter Fuhr, Prof. University Hospital Basel, Neurology
  More Information

No publications provided

Responsible Party: University Hospital, Basel, Switzerland
ClinicalTrials.gov Identifier: NCT01393353     History of Changes
Other Study ID Numbers: UHBS
Study First Received: July 6, 2011
Last Updated: December 12, 2014
Health Authority: Switzerland: Swissmedic

ClinicalTrials.gov processed this record on April 16, 2015