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Heart Rate Variability During Sleep After Fast-track Surgery

This study has been completed.
Information provided by (Responsible Party):
Lene Krenk, Rigshospitalet, Denmark Identifier:
First received: July 11, 2011
Last updated: December 13, 2011
Last verified: December 2011
Based on prior findings concerning sleep disturbances, in particular REM sleep disturbances, after fast-track hip and knee arthroplasty (H-2-2010-011) we performed a supplemental analysis of heart rate variablity after arousals during sleep. We compared preoperative and postoperative results.

Heart Rate Variablity

Study Type: Observational
Study Design: Time Perspective: Prospective

Further study details as provided by Lene Krenk, Rigshospitalet, Denmark:

Primary Outcome Measures:
  • heart rate variability [ Time Frame: 24 hours ]
    heart rate variability measured 5 beats before arousel and 15 beats after arousel in different sleep stages.

Enrollment: 10
Study Start Date: July 2011
Study Completion Date: December 2011
Primary Completion Date: December 2011 (Final data collection date for primary outcome measure)
patient characteristics are specified in H-2-2010-011
age matched to patients described in protocol H-2-2010-011


Ages Eligible for Study:   60 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
We selected patients undergoing fasttrack hip and knee arthoplasty in fast-track setip. The underwent sleep monotoring for 1 preoperative night and continously during hospitalisation, and for 1 night at home after surgery.

Inclusion criteria (for the control group):

  • Age > 60 years

Exclusion criteria:

  • surgery within the last 2 months
  • known sleep disorder (eg. sleep apnea)
  • daily beta blocker treatment
  • daily dopamine treatment

This protocol only concentrates on the healthy controls for the patient described in H-2-2010-011.

  Contacts and Locations
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Please refer to this study by its identifier: NCT01393236

Copenhagen, Denmark
Sponsors and Collaborators
Lene Krenk
Principal Investigator: Lene Krenk, MD Rigshospitalet, Denmark
  More Information

Responsible Party: Lene Krenk, Doctor, Rigshospitalet, Denmark Identifier: NCT01393236     History of Changes
Other Study ID Numbers: H-2-2010-011a
Study First Received: July 11, 2011
Last Updated: December 13, 2011 processed this record on August 18, 2017