Epigenetics of Posttraumatic Stress Disorder and Somatoform Disorders in the Course of Psychotherapy (TREPS)
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|ClinicalTrials.gov Identifier: NCT01391897|
Recruitment Status : Unknown
Verified June 2011 by Hannover Medical School.
Recruitment status was: Recruiting
First Posted : July 12, 2011
Last Update Posted : July 12, 2011
This reported observational clinical study aims at identifying epigenetic markers in a sample of patients undergoing high dose inpatient psychotherapy suffering from a variety of psychiatric/psychosomatic diseases such as somatoform disorders, posttraumatic stress disorder (PTSD), depression, anxiety disorders and eating disorders.
The exact epigenetic markers that will be traced are yet to define.
The investigators believe that
- Epigenetic patterns found in the group of psychiatric patients show differences from healthy controls
- Different diagnosis show differences in epigenetic patterns as well
- Epigenetic patterns correlate to the severity of the psychosocial disorder as measured in interviews or psychometric ratings
- Epigenetic patterns can change under inpatient high dose psychotherapy
- Changes correlate to clinical psychometric variables.
|Condition or disease||Intervention/treatment|
|Psychiatric Disorder Somatoform Disorders PTSD||Behavioral: psychotherapy|
|Study Type :||Observational|
|Estimated Enrollment :||300 participants|
|Study Start Date :||January 2011|
|Estimated Primary Completion Date :||January 2012|
|Estimated Study Completion Date :||September 2012|
in- and out-patient psychotherapy patients
All included patients are highly selected in- and outpatients in a department of psychosomatic medicine (Germany) undergoing high dose psychotherapy (e.g. group therapy, creative therapy, cbt and psychodynamic psychotherapy).
"multimodal complex psychotherapy"
Other Name: all patients in the department are primarily included. There are no parallel groups.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01391897
|Hannover, Lower Saxony, Germany, 30625|
|Contact: Stefan M Henniger, MD 49 511 532 ext 6446 Henniger.Stefan@MH-Hannover.de|
|Contact: Frieling, Prof. 49 511 532 ext 6840 Frieling.Helge@mh-hannover.de|