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ClinicalTrials.gov Identifier: NCT01388894
Verified May 2011 by Glostrup University Hospital, Copenhagen. Recruitment status was: Recruiting
Patients who report that exposure to bright light or strenuous physical activity will induce migraine aura will be provoked using one or both of these methods. Followingly the patients will be examined by functional MRI. Íf the patients develop migraine headache, MR angiography will be performed as well. The primary study hypothesis is that the functional MRI signal will show features similar to those of the electrophysiological phenomenon of cortical spreading depression.
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Ages Eligible for Study:
18 Years to 80 Years (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Patients diagnosed with migraine with aura
Diagnosed with migraine with aura as defined by The International Classification of Headache Disorders 2
Age between 18 and 80 years both inclusive
Reports that bright light or strenuous physical activity may trigger migraine aura
Contraindications towards exposure to photostimulation or strenuous exercise
Body weight above 130 kg
Pregnant or lactating females
Contraindications towards MRI scanning
History or clinical signs of: cardiovascular disease, psychiatric disease, substance abuse or any symptom or disease considered relevant by the examining physician.