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The Incidence,Factors,and Importance of Brown Adipose Tissue in Chinese Adults

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified November 2009 by Huashan Hospital.
Recruitment status was:  Active, not recruiting
Information provided by:
Huashan Hospital Identifier:
First received: June 30, 2011
Last updated: July 1, 2011
Last verified: November 2009
Previous studies have shown that active brown adipose tissue (BAT) is present in adults and may play important roles in material and energy metabolism. However, most of these studies were tumor-based populations and retrospective study. Due to the large amount in our cohort, the investigators are able to promote a cross-sectional study of the incidence and factors of BAT in adult chinese. In addition, the investigators can analyse the metabolic profiles in healthy adults with active BAT.


Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Cross-Sectional
Official Title: Cross-sectional Study on the Incidence,Factors,and Importance of Brown Adipose Tissue in Adult Chinese

Further study details as provided by Huashan Hospital:

Biospecimen Retention:   Samples Without DNA

Estimated Enrollment: 200
Study Start Date: December 2009
Estimated Study Completion Date: December 2013
Estimated Primary Completion Date: December 2013 (Final data collection date for primary outcome measure)
Detailed Description:
The investigators will perform a cross sectional analysis on the chinese adults who use 18F-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) to scan the whole body at Huashan Hospital from 2009 to 2013. BAT activity will be measured by PET/CT. Not only demographic data on sex, age, medication and medical history,but also data on body composition and physical examination will be collected for all subjects. Imaging date,outdoor temperature and fasting blood samples will be collected as well. In addition, the investigators will analyse the metabolic profiles in healthy adults with active BAT and their negative controls,such as lipid profiles,fasting glucose and insulin sensitivity, adipokines and other biochemical markers.

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Subjects who underwent scanning PET-CT at Huashan Hospital Medical Centre from 2009 to 2013

Inclusion Criteria:

  • Subjects with detectable brown adipose tissue
  • Negative controls,consisting of one subject who underwent PET/CT scans at the same day but without detectable BAT

Exclusion Criteria:

  • Younger than 18 years
  • Pregnant women
  • With implantable medical electronic instrument
  Contacts and Locations
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Please refer to this study by its identifier: NCT01387438

China, Shanghai
Huashan Hospital
Shanghai, Shanghai, China, 200040
Sponsors and Collaborators
Huashan Hospital
Study Chair: Yiming Li, Doctor Huashan Hospital
  More Information

Responsible Party: Yiming Li, Huashan Hospital Identifier: NCT01387438     History of Changes
Other Study ID Numbers: KY2009-279
Study First Received: June 30, 2011
Last Updated: July 1, 2011

Keywords provided by Huashan Hospital:
Brown Adipose Tissue
Cross sectional study
Chinese Adults
Factor processed this record on September 19, 2017