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Impact of Spontaneous Breathing on Ventilation Distribution in Obese Patients

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified June 2011 by Technische Universität Dresden.
Recruitment status was:  Recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT01382927
First Posted: June 27, 2011
Last Update Posted: June 27, 2011
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Technische Universität Dresden
  Purpose
General anesthesia (GA) and paralysis are factors which facilitate atelectasis formation, especially in obese patients. Spontaneous breathing can reduce the amount of atelectasis. In this study, the investigators are comaparing obese patients undergoing hip arthroplasty in GA versus spinal anesthesia. Distribution of ventilation during and after anesthesia is assessed by eletrical impedance tomography (EIT).

Condition
Obesity Hip Arthroplasty General Anesthesia Spinal Anesthesia Atelectasis

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Impact of Spontaneous Breathing on Ventilation Distribution in Obese Patients

Resource links provided by NLM:


Further study details as provided by Technische Universität Dresden:

Primary Outcome Measures:
  • arterial pO2 on room air [ Time Frame: 24hrs ]
  • Center of Ventilation [ Time Frame: 24hrs ]
    measured by EIT


Secondary Outcome Measures:
  • Peak Flow [ Time Frame: 24hrs ]

Estimated Enrollment: 16
Study Start Date: April 2011
Groups/Cohorts
General Anesthesia
Spinal Anesthesia

  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years to 85 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Obese Patients aged 18-85, scheduled for elective hip arthroplasty
Criteria

Inclusion Criteria:

  • BMI >30
  • age 18-85
  • elective hip arthroplasty in general anesthesia or spinal anesthesia

Exclusion Criteria:

  • pregnancy/breastfeeding
  • allergies against drugs used for the anesthesia
  • contraindications for EIT
  • severe cardiac or pulmonary comorbidities
  • unable to consent or understand/follow study
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01382927


Locations
Germany
University Hospital Carl-Gustav-Carus Recruiting
Dresden, Germany, 01307
Contact: Oliver C Radke, MD, PhD, DEAA    +49 351 458-18040    oradke@pcat.de   
Principal Investigator: Oliver C Radke, MD, PhD, DEAA         
Sponsors and Collaborators
Technische Universität Dresden
  More Information

Responsible Party: Oliver C. Radke, MD, PhD, DEAA, Dpt of Anesthesia and Perioperative Care
ClinicalTrials.gov Identifier: NCT01382927     History of Changes
Other Study ID Numbers: SBVOBP
First Submitted: June 22, 2011
First Posted: June 27, 2011
Last Update Posted: June 27, 2011
Last Verified: June 2011

Additional relevant MeSH terms:
Pulmonary Atelectasis
Lung Diseases
Respiratory Tract Diseases