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Impact of Spontaneous Breathing on Ventilation Distribution in Obese Patients

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ClinicalTrials.gov Identifier: NCT01382927
Recruitment Status : Unknown
Verified June 2011 by Technische Universität Dresden.
Recruitment status was:  Recruiting
First Posted : June 27, 2011
Last Update Posted : June 27, 2011
Information provided by:
Technische Universität Dresden

Brief Summary:
General anesthesia (GA) and paralysis are factors which facilitate atelectasis formation, especially in obese patients. Spontaneous breathing can reduce the amount of atelectasis. In this study, the investigators are comaparing obese patients undergoing hip arthroplasty in GA versus spinal anesthesia. Distribution of ventilation during and after anesthesia is assessed by eletrical impedance tomography (EIT).

Condition or disease
Obesity Hip Arthroplasty General Anesthesia Spinal Anesthesia Atelectasis

Study Type : Observational
Estimated Enrollment : 16 participants
Observational Model: Case Control
Time Perspective: Prospective
Official Title: Impact of Spontaneous Breathing on Ventilation Distribution in Obese Patients
Study Start Date : April 2011

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Anesthesia
U.S. FDA Resources

General Anesthesia
Spinal Anesthesia

Primary Outcome Measures :
  1. arterial pO2 on room air [ Time Frame: 24hrs ]
  2. Center of Ventilation [ Time Frame: 24hrs ]
    measured by EIT

Secondary Outcome Measures :
  1. Peak Flow [ Time Frame: 24hrs ]

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 85 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Obese Patients aged 18-85, scheduled for elective hip arthroplasty

Inclusion Criteria:

  • BMI >30
  • age 18-85
  • elective hip arthroplasty in general anesthesia or spinal anesthesia

Exclusion Criteria:

  • pregnancy/breastfeeding
  • allergies against drugs used for the anesthesia
  • contraindications for EIT
  • severe cardiac or pulmonary comorbidities
  • unable to consent or understand/follow study

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01382927

University Hospital Carl-Gustav-Carus Recruiting
Dresden, Germany, 01307
Contact: Oliver C Radke, MD, PhD, DEAA    +49 351 458-18040    oradke@pcat.de   
Principal Investigator: Oliver C Radke, MD, PhD, DEAA         
Sponsors and Collaborators
Technische Universität Dresden

Responsible Party: Oliver C. Radke, MD, PhD, DEAA, Dpt of Anesthesia and Perioperative Care
ClinicalTrials.gov Identifier: NCT01382927     History of Changes
Other Study ID Numbers: SBVOBP
First Posted: June 27, 2011    Key Record Dates
Last Update Posted: June 27, 2011
Last Verified: June 2011

Additional relevant MeSH terms:
Pulmonary Atelectasis
Lung Diseases
Respiratory Tract Diseases