Determination of the Pathophysicologic Collagen Changes in the Diabetic Achilles Tendon
|ClinicalTrials.gov Identifier: NCT01382628|
Recruitment Status : Suspended (We are currently trying to find someone to assay the collagen)
First Posted : June 27, 2011
Last Update Posted : July 11, 2017
|Condition or disease|
|Diabetic Foot Ulcers Equinus Deformity|
Show Detailed Description
|Study Type :||Observational|
|Estimated Enrollment :||50 participants|
|Official Title:||Determination of the Pathophysicologic Collagen Changes in the Diabetic Achilles Tendon.|
|Study Start Date :||May 2011|
|Estimated Primary Completion Date :||May 2018|
|Estimated Study Completion Date :||May 2018|
Preulcerative plantar foot lesion
An area on the plantar foot, usually at the location of a bony prominence, that presents with erythema, significant hyperkeratosis, or thin, shiny skin.
Plantar ulcer no history of amputation
Plantar ulceration without a history of amputation or require an amputation.
Plantar ulcer and digital amputation
Plantar ulceration who will be undergoing a digital amputation.
Plantar ulcer and transmet amputation
Plantar ulceration who will be undergoing a transmetatarsal amputation.
Plantar ulceration and choparts
Plantar ulceration who will be undergoing Chopart's or more proximal amputation.
- Structural and metabolic changes [ Time Frame: 1 year ]Characterize the structural and metabolic changes in the diabetic Achilles tendon as related to limb loss.
- Relationship between collagen changes and system changes [ Time Frame: 1 year ]Describe the relationship between collagen changes and system changes in the diabetic patient.
Biospecimen Retention: Samples Without DNA
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01382628
|United States, District of Columbia|
|Georgetown University Hospital Center for Wound Healing|
|Washington, D.C., District of Columbia, United States, 20007|
|Principal Investigator:||Paul J. Kim, DPM||Georgetown University Hospital|