Determination of the Pathophysicologic Collagen Changes in the Diabetic Achilles Tendon
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|ClinicalTrials.gov Identifier: NCT01382628|
Recruitment Status : Suspended (We are currently trying to find someone to assay the collagen)
First Posted : June 27, 2011
Last Update Posted : July 11, 2017
|Condition or disease|
|Diabetic Foot Ulcers Equinus Deformity|
Show Detailed Description
|Study Type :||Observational|
|Estimated Enrollment :||50 participants|
|Official Title:||Determination of the Pathophysicologic Collagen Changes in the Diabetic Achilles Tendon.|
|Study Start Date :||May 2011|
|Estimated Primary Completion Date :||May 2018|
|Estimated Study Completion Date :||May 2018|
Preulcerative plantar foot lesion
An area on the plantar foot, usually at the location of a bony prominence, that presents with erythema, significant hyperkeratosis, or thin, shiny skin.
Plantar ulcer no history of amputation
Plantar ulceration without a history of amputation or require an amputation.
Plantar ulcer and digital amputation
Plantar ulceration who will be undergoing a digital amputation.
Plantar ulcer and transmet amputation
Plantar ulceration who will be undergoing a transmetatarsal amputation.
Plantar ulceration and choparts
Plantar ulceration who will be undergoing Chopart's or more proximal amputation.
- Structural and metabolic changes [ Time Frame: 1 year ]Characterize the structural and metabolic changes in the diabetic Achilles tendon as related to limb loss.
- Relationship between collagen changes and system changes [ Time Frame: 1 year ]Describe the relationship between collagen changes and system changes in the diabetic patient.
Biospecimen Retention: Samples Without DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01382628
|United States, District of Columbia|
|Georgetown University Hospital Center for Wound Healing|
|Washington, D.C., District of Columbia, United States, 20007|
|Principal Investigator:||Paul J. Kim, DPM||Georgetown University Hospital|