Immunolabeling Evaluation of Five Selected Markers in Skin Biopsies of Patients With Postherpetic Neuralgia and Healthy Controls (STTR)
Recruitment status was: Recruiting
Postherpetic Neuralgia is a painful nerve condition that can occur when nerve fibers are damaged following an outbreak of shingles.
The purpose of this study is to identify and study abnormalities in the nerves and cells in the of patients with postherpetic Neuralgia (PHN) and characterize changes that could be responsible for causing nerve pain. This data will be compared to the tissue of healthy volunteers. Our goal is that this information will lead to the development of better treatment options for people with painful nerve conditions.
Healthy Age/Gender Matched Volunteers
Other: skin biopsy
|Study Design:||Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Diagnostic
|Official Title:||Immunolabeling Evaluation of Five Selected Markers in Skin Biopsies of Patients With Postherpetic Neuralgia (PHN) and Age and Gender-Matched Normal Controls|
- use of genetic data to enhance the search for targeted therapeutic approaches to chronic pain management [ Time Frame: One year ] [ Designated as safety issue: No ]The skin biopsies will be used to identify the site of expression of selected makers in skin, including nerve fibers and skin substructures in patients with PHN and age and gender-atched normal controls.
|Study Start Date:||January 2011|
|Estimated Primary Completion Date:||January 2012 (Final data collection date for primary outcome measure)|
Other: skin biopsy
Please refer to this study by its ClinicalTrials.gov identifier: NCT01379716
|United States, New York|
|Albany Medical College|
|Albany, New York, United States, 12208|
|Principal Investigator:||James P. Wymer, MD||Albany Medical College|