Best Cardiac Output During Cardiopulmonary Bypass
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|ClinicalTrials.gov Identifier: NCT01379638|
Recruitment Status : Completed
First Posted : June 23, 2011
Last Update Posted : June 23, 2011
|Condition or disease|
For more than 50 years, CPB has been used to mechanically support the functions of the heart and lungs. In early studies, systemic oxygen uptake, calculated using Ficks global principle, was used to assess the efficiency of CPB. Using this measure of efficiency, a pump flow rate in liters per minute, based on the product of the body surface area (BSA) and a constant of 2.4 was found adequate to perfuse the body during normothermia. Ficks global principle is still used together with other methods to secure adequated perfusion under CPB.
The purpose of this study is to determine whether the patients cardiac output measured before CPB, is more sufficient to secure the patients oxygen needs than the estimated cardiac output from Ficks principle, and thereby prevent organ failure.
The hypothesis is that the patients cardiac output is a better marker for the optimal cardiac output than the estimated cardiac output.
|Study Type :||Observational|
|Actual Enrollment :||20 participants|
|Observational Model:||Case Control|
|Official Title:||Best Cardiac Output During Cardiopulmonary Bypass|
|Study Start Date :||December 2008|
|Actual Primary Completion Date :||January 2010|
|Actual Study Completion Date :||January 2010|
Adult patients undergoing cardiac surgery with normothermic cardiopulmonary bypass
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01379638
|Aalborg, Denmark, 9100|
|Study Director:||Bodil Steen Rasmussen, MD, PhD||Aalborg Universitetshospital|