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The Observational Study of Growth Hormone-secreting Pituitary Tumors

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ClinicalTrials.gov Identifier: NCT01368133
Recruitment Status : Unknown
Verified September 2013 by Zhaoyun Zhang, Huashan Hospital.
Recruitment status was:  Recruiting
First Posted : June 7, 2011
Last Update Posted : September 26, 2013
Sponsor:
Collaborator:
National Natural Science Foundation of China
Information provided by (Responsible Party):
Zhaoyun Zhang, Huashan Hospital

Brief Summary:
The major purpose of this study is to evaluate the changes of multiple organs in patients with growth hormone-secreting pituitary tumors before and after surgery. Plasma, DNA samples and pituitary tumor tissues will be kept for further analysis.

Condition or disease
Acromegaly Pituitary Tumor

Detailed Description:
Multiple organs or systems will be affected by excessive growth hormones in patients with acromegaly. The major purpose of this study is to evaluate the changes before and after the pituitary surgery.

Study Type : Observational
Estimated Enrollment : 60 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: The Observational Study of the Structures and Functions of Multiple Organs in Patients With Growth Hormone-secreting Tumors
Study Start Date : May 2011
Estimated Primary Completion Date : December 2013
Estimated Study Completion Date : December 2013





Biospecimen Retention:   Samples With DNA
Plasma, DNA and pituitary tumor tissues


Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 70 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
The acromegaly patients at Huashan Hospital will be recruited anf followed up prior to surgery and one month, 3 months, 6 months and 12 months after surgery.
Criteria

Inclusion Criteria:

  • Clinical diagnosis of acromegaly
  • > 18 years old

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01368133


Contacts
Contact: Jiahui Qiu, M.D. 86-13585951850 qiuhuijiaatsjtu@163.com
Contact: zhaoyun zhang, M.D. 86-21-52888286 zhaoyunzhang@fudan.edu.cn

Locations
China
Huashan Hospital Recruiting
Shanghai, China, 200040
Contact: Cuiyun Wu    86-21-52888047    hskyc@fudan.edu.cn   
Contact: Zhaoyun Zhang    86-21-52888286    zhaoyunzhang@fudan.edu.cn   
Principal Investigator: Yao Zhao, M.D.         
Sponsors and Collaborators
Huashan Hospital
National Natural Science Foundation of China
Investigators
Principal Investigator: Yao Zhao, M.D. Huashan Hospital

Responsible Party: Zhaoyun Zhang, Associate Professor, Huashan Hospital
ClinicalTrials.gov Identifier: NCT01368133     History of Changes
Other Study ID Numbers: 2010M-010
First Posted: June 7, 2011    Key Record Dates
Last Update Posted: September 26, 2013
Last Verified: September 2013

Keywords provided by Zhaoyun Zhang, Huashan Hospital:
acromegaly
pituitary tumor

Additional relevant MeSH terms:
Pituitary Neoplasms
Pituitary Diseases
Acromegaly
Hypothalamic Diseases
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Endocrine System Diseases
Bone Diseases, Endocrine
Bone Diseases
Musculoskeletal Diseases
Hyperpituitarism
Endocrine Gland Neoplasms
Neoplasms by Site
Neoplasms
Hypothalamic Neoplasms
Supratentorial Neoplasms
Brain Neoplasms
Central Nervous System Neoplasms
Nervous System Neoplasms
Hormones
Hormones, Hormone Substitutes, and Hormone Antagonists
Physiological Effects of Drugs