Biomarker in Tissue Samples From Patients With Ewing Sarcoma
RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
PURPOSE: This research trial studies biomarkers in tissue samples from patients with Ewing sarcoma.
Genetic: microarray analysis
Genetic: protein analysis
Other: immunohistochemistry staining method
Other: laboratory biomarker analysis
|Study Design:||Observational Model: Case-Only
Time Perspective: Retrospective
|Official Title:||INI-1 Deletions in Ewing Sarcoma|
- Frequency of INI1 protein loss in Ewing Sarcoma [ Designated as safety issue: No ]
Biospecimen Retention: Samples With DNA
|Study Start Date:||May 2011|
|Primary Completion Date:||July 2016 (Final data collection date for primary outcome measure)|
- To determine the frequency of INI-1 protein loss in Ewing Sarcoma.
OUTLINE: Previously collected tissue samples are analyzed for INI-1 protein loss by IHC and tissue microarray.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01365949
|Principal Investigator:||Joshua D. Schiffman, MD||University of Utah|