Bladder Pressure Predicting Renal Failure in Critically Ill Patients as Compared to Hemodynamic Parameters
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|ClinicalTrials.gov Identifier: NCT01363505|
Recruitment Status : Completed
First Posted : June 1, 2011
Last Update Posted : February 3, 2014
Studies have shown that more than 30% of the overall acute decompensated heart failure (ADHF) patients develop renal dysfunction.
Several studies have tried to find a correlation between hemodynamic Parameters (blood pressure , heart rate, central venous pressure CVP) and worsening of renal function in acute decompensated heart failure patients.
Results showed that there were no correlation between baseline hemodynamics or change in hemodynamics and worsening of renal function.
Another study showed that intra-abdominal pressure (IAP) measuring was a better corollary to renal failure status then measuring cardiovascular hemodynamics using pulmonary artery catheterization in ADHF patients.. An increased IAP was associated with worse renal function and that level of IAP far below abdominal compartment syndrome may adversely affect renal function in patients with ADHF.
|Condition or disease||Intervention/treatment|
|Acute Heart Failure Acute Renal Failure||Device: BARD® Intra-abdominal Pressure monitor|
|Study Type :||Observational|
|Actual Enrollment :||16 participants|
|Observational Model:||Case Control|
|Official Title:||Is Intravesicular Pressure a Better Tool to Predict Renal Failure in Critically Ill Patients Compared With Routine Hemodynamic Parameters?|
|Study Start Date :||May 2011|
|Actual Primary Completion Date :||April 2013|
|Actual Study Completion Date :||April 2013|
Acute CHF patients
Acute CHF patients with BARD Intra-abdominal pressure monitors in ICU
Device: BARD® Intra-abdominal Pressure monitor
monitor linked to foley catheter that is able to measure pressure inside bladder
- High intraabdominal pressure and effect on renal function [ Time Frame: from admission (baseline) until 72 hours later ]IAP measurements will be recorded concomitantly with renal indices. Correlations will be made in regard to pressure measurements and worsening renal function.
- Effect of diuretics use on intrabdominal pressure [ Time Frame: 3 days from admission ]Early initiation of diuretics in acute heart failure improvement correlating with decreasing IAP measurements.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01363505
|United States, New York|
|Staten Island University Hospital|
|Staten Island, New York, United States, 10305|
|Study Director:||Suzanne El-Sayegh, MD||Staten Island University Hospital|