Orthostatic Hypotension in Elderly Nursing Home Residents

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01362751
Recruitment Status : Completed
First Posted : May 30, 2011
Last Update Posted : September 5, 2012
Information provided by (Responsible Party):
Kornelis J.J. van Hateren, Medical Research Foundation, The Netherlands

Brief Summary:

In this study the investigators aimed

  1. to investigate the prevalence of orthostatic hypotension in elderly nursing home residents.
  2. to investigate whether the presence of orthostatic hypotension influences the chance of successful rehabilitation.

Condition or disease Intervention/treatment
Orthostatic Hypotension Other: No intervention

Study Type : Observational
Actual Enrollment : 290 participants
Observational Model: Cohort
Study Start Date : October 2010
Actual Primary Completion Date : March 2012
Actual Study Completion Date : March 2012

Resource links provided by the National Library of Medicine

Group/Cohort Intervention/treatment
Nursing home residents
In this study, patients from both the somatic and the psychogeriatric department are included. For the primary endpoint 'successful rehabilitation' only the patients from the somatic departments are included.
Other: No intervention
This study is an observational cohort study > no interventions

Primary Outcome Measures :
  1. Orthostatic hypotension [ Time Frame: Baseline ]
    Orthostatic hypotension is defined by consensus as a fall in blood pressure of at least 20 mmHg systolic or 10 mmHg diastolic within 3 minutes in the upright position

  2. Successful rehabilitation [ Time Frame: After 5 years ]
    Successful rehabilitation is defined as whether the patient is able to return to his/her home or another location (but not a nursing home) after discharge from the nursing home. Unsuccessful rehabilitations implies that the patients becomes a long-stay nursing home resident.

Secondary Outcome Measures :
  1. All-cause and Cardiovascular mortality [ Time Frame: Date of death ]
  2. Quality of life [ Time Frame: Measured at baseline and after 1 year ]
    Quality of life is measured using the RAND-36 questionnaire.

  3. Fall incidents [ Time Frame: After 5 years ]

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Nursing home residents

Inclusion Criteria:

  • nursing home resident

Exclusion Criteria:

  • patients at the palliative department
  • life expectancy < 4 weeks
  • patients only temporarily admitted to the nursing home

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01362751

Nursing home TriviumMeulenbeltZorg, location Borsthuis
Hengelo, Netherlands
Sponsors and Collaborators
Medical Research Foundation, The Netherlands

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Kornelis J.J. van Hateren, MD, Medical Research Foundation, The Netherlands Identifier: NCT01362751     History of Changes
Other Study ID Numbers: OH_TMZ_2010
First Posted: May 30, 2011    Key Record Dates
Last Update Posted: September 5, 2012
Last Verified: September 2012

Additional relevant MeSH terms:
Hypotension, Orthostatic
Vascular Diseases
Cardiovascular Diseases
Orthostatic Intolerance
Primary Dysautonomias
Autonomic Nervous System Diseases
Nervous System Diseases