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Analgesia After Cesarean Section

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ClinicalTrials.gov Identifier: NCT01360060
Recruitment Status : Completed
First Posted : May 25, 2011
Last Update Posted : May 25, 2011
Sponsor:
Information provided by:
Seoul National University Bundang Hospital

Brief Summary:
Magnesium sulphate is the first line therapy for the management of preeclampsia and eclampsia in obstetrics. Perioperative administration of magnesium sulphate has been proved to be an effective as an analgesic adjuvant. The investigators evaluated the analgesic effect of magnesium in parturients undergoing Cesarean section.

Condition or disease Intervention/treatment
Preeclampsia Pregnancy Drug: Magnesium Sulphate

Study Type : Observational
Actual Enrollment : 503 participants
Observational Model: Case Control
Time Perspective: Retrospective
Study Start Date : December 2010
Primary Completion Date : March 2011
Study Completion Date : March 2011

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Cesarean Section
U.S. FDA Resources

Group/Cohort Intervention/treatment
Group N
parturients who had undergone Cesarean section under the diagnosis of non-preeclampsia
Group P
parturients who had undergone Cesarean section under the diagnosis of preeclampsia
Drug: Magnesium Sulphate
Magnesium sulphate was infused for the management of preeclampsia at perioperative period.



Primary Outcome Measures :
  1. Change of numeric rating scale (NRS) of postoperative pain during postoperative period [ Time Frame: postoperative 1, 2, 3, and 4 day ]

Secondary Outcome Measures :
  1. incidence of stopping of intravenous PCA during postoperative 4 days [ Time Frame: during postoperative 4 days ]
  2. serum magnesium level of group P [ Time Frame: preoperative 1 h and postoperative 1 day ]


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Ages Eligible for Study:   20 Years to 50 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
medical record review
Criteria

Inclusion Criteria:

  • parturients undergoing Cesarean section

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01360060


Locations
Korea, Republic of
Seoul national university bundang hospital
Seongnam, Gyeonggi, Korea, Republic of
Sponsors and Collaborators
Seoul National University Bundang Hospital

Responsible Party: Hyoseok, Na/professor, Seoul National University Bundang Hospital
ClinicalTrials.gov Identifier: NCT01360060     History of Changes
Other Study ID Numbers: Mg_section
First Posted: May 25, 2011    Key Record Dates
Last Update Posted: May 25, 2011
Last Verified: May 2011

Additional relevant MeSH terms:
Pre-Eclampsia
Hypertension, Pregnancy-Induced
Pregnancy Complications
Magnesium Sulfate
Analgesics
Sensory System Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
Anesthetics
Central Nervous System Depressants
Anti-Arrhythmia Agents
Anticonvulsants
Calcium Channel Blockers
Membrane Transport Modulators
Molecular Mechanisms of Pharmacological Action
Tocolytic Agents
Reproductive Control Agents