Costimulatory Molecules as Biomarkers in Cystic Fibrosis

The recruitment status of this study is unknown because the information has not been verified recently.
Verified July 2011 by Oregon Health and Science University.
Recruitment status was  Recruiting
Information provided by:
Oregon Health and Science University Identifier:
First received: May 12, 2011
Last updated: July 19, 2011
Last verified: July 2011
The purpose of this study is to investigate the expression of a certain class of molecules, called costimulatory molecules, in humans with Cystic Fibrosis. Cystic Fibrosis is a genetic disorder which renders the lung susceptible to persistent inflammation which, at times, can worsen, resulting in accelerated decline in lung function and eventually death or transplant. Our goal is to determine if the levels of costimulatory markers can be used to predict exacerbation and subsequent lung function decline in subjects with Cystic Fibrosis.

Cystic Fibrosis

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Costimulatory Molecules as Biomarkers in Cystic Fibrosis

Resource links provided by NLM:

Further study details as provided by Oregon Health and Science University:

Biospecimen Retention:   Samples Without DNA
Plasma, Serum, urine

Estimated Enrollment: 40
Study Start Date: July 2011
Estimated Study Completion Date: June 2013
Estimated Primary Completion Date: June 2013 (Final data collection date for primary outcome measure)
Adult Cystic Fibrosis Patients
Adults with Cystic Fibrosis will be followed longitudinally for 2 years


Ages Eligible for Study:   18 Years to 80 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Adults with Cystic Fibrosis

Inclusion Criteria:

  • Willingness to participate

Exclusion Criteria:

  • Presence of HIV
  • Presence of Lymphoma/Leukemia
  • Presence of Lung or other solid organ Transplant
  • Pregnancy
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01353950

Contact: Jeffrey A Gold, MD 5034181496

United States, Oregon
Oregon health and Sciences University Recruiting
Portland, Oregon, United States, 97239
Contact: Jeffrey A GOld, MD    503-418-1496   
Principal Investigator: Jeffrey A GOld, MD         
Sponsors and Collaborators
Oregon Health and Science University
  More Information

Responsible Party: Jeffrey A. Gold, MD, Oregon health and Sciences University Identifier: NCT01353950     History of Changes
Other Study ID Numbers: IRB00007132 
Study First Received: May 12, 2011
Last Updated: July 19, 2011
Health Authority: United States: Institutional Review Board

Keywords provided by Oregon Health and Science University:
Costimulatory molecules
Cystic Fibrosis

Additional relevant MeSH terms:
Cystic Fibrosis
Digestive System Diseases
Genetic Diseases, Inborn
Infant, Newborn, Diseases
Lung Diseases
Pancreatic Diseases
Pathologic Processes
Respiratory Tract Diseases processed this record on May 25, 2016