Intraoperative Posterior Cruciate Ligament (Transcruciate) Injection After Total Knee Arthroplasty (TKA)
|ClinicalTrials.gov Identifier: NCT01345604|
Recruitment Status : Completed
First Posted : May 2, 2011
Last Update Posted : November 15, 2016
his study is being done because total knee replacements can leave patients with considerable pain after surgery. Therefore, many studies have been done to find the best ways to control knee pain after the surgery. Currently, a popular approach is to use many different techniques to control the pain. This includes injecting freezing (local anesthetic) into the spinal column (spinal anesthetic), injecting freezing close to the nerves of the knee and using various kinds of medications (e.g. narcotics and anti-inflammatory medications). Studies have shown using this a combination of techniques can reduce pain and allow earlier discharge from the hospital. However, one downside to this approach is it does not usually control the pain in the back of the knee. One new technique has been used to try and overcome this. This technique is called a "posterior cruciate ligament block" or "PCL block". It involves injecting a drug into the back of the knee which will block the nerves in this area. Sometimes the investigators refer to this as "freezing".
The purpose of our study is to determine whether this "PCL Block" will improve pain after the total knee replacement surgery. The investigators will also determine whether this technique will improve movement in the knee and lessen narcotic usage after the surgery.
|Condition or disease||Intervention/treatment||Phase|
|Arthroplasty, Replacement, Knee||Procedure: transcruciate injection of 20cc of normal saline Procedure: transcruciate injection of 20 cc of 0.5% Ropivacaine||Phase 4|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||50 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)|
|Official Title:||Reducing Posterior Knee Pain Following Total Knee Arthroplasty Using an Intraoperative Posterior Cruciate Ligament (Transcruciate) Injection|
|Study Start Date :||May 2011|
|Actual Primary Completion Date :||May 2013|
|Actual Study Completion Date :||May 2013|
|Placebo Comparator: Saline||
Procedure: transcruciate injection of 20cc of normal saline
Group 2 (control group) will receive a transcruciate injection of 20cc of normal saline through the posterior cruciate ligament during the procedure (in addition to a subarachnoid block and femoral nerve block pre-operatively).
|Active Comparator: Ropivicaine||
Procedure: transcruciate injection of 20 cc of 0.5% Ropivacaine
Group 1 (study group) will receive a transcruciate injection of 20 cc of 0.5% Ropivacaine through the posterior cruciate ligament during the procedure (in addition to a subarachnoid block and femoral nerve block pre-operatively).
- Knee flexion [ Time Frame: up to one week postoperative ]
- Postoperative pain score [ Time Frame: in PACU , on ward (baseline), and post-op day 1 & 2 at 10am & 6pm ]Pain scores will be recorded at rest and on attempt of achieving a 90 degree passive flexion of the knee.
- Total narcotic consumption [ Time Frame: up to 1 week postoperative ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01345604
|Saskatoon City Hospital|
|Saskatoon, Saskatchewan, Canada, S7K 5T6|