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Impact of Current Smoking in the Tolerance of Bronchoscopy

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ClinicalTrials.gov Identifier: NCT01345383
Recruitment Status : Terminated (the physician responsable for this protocol left our hospital)
First Posted : May 2, 2011
Last Update Posted : March 10, 2015
Sponsor:
Information provided by (Responsible Party):
Marie Bruyneel, Centre Hospitalier Universitaire Saint Pierre

Brief Summary:
The purpose of this study is to study the impact of smoking in the preceding hours before a bronchoscopy on the tolerance of this exam.

Condition or disease Intervention/treatment
Smokers Procedure: bronchoscopy

Detailed Description:

Tolerance evaluation of the bronchoscopy on current and regular smokers. The investigators assess episodes of cough, dyspnea, volume of lidocain (liquid 1% and in spray 10%), duration of the procedure, episodes of desaturation and completion of the bronchoscopy.

The investigators compare patients who did not smoke in the 6 hours before the bronchoscopy and those who have smoked.


Study Type : Observational
Actual Enrollment : 100 participants
Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Impact of Current Smoking in the Tolerance of Bronchoscopy
Study Start Date : June 2010
Actual Primary Completion Date : August 2013
Actual Study Completion Date : August 2013

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Smoking
U.S. FDA Resources

Group/Cohort Intervention/treatment
Current smokers Procedure: bronchoscopy
Routine bronchoscopy under local anesthesia (lidocain). Duration: +/- 10 min



Primary Outcome Measures :
  1. cough [ Time Frame: Day 1 ]
    number of cough episodes during the bronchoscopy


Secondary Outcome Measures :
  1. dyspnea [ Time Frame: day 1 ]
    dyspnea evaluation before and during the bronchoscopy

  2. Lidocaine volume [ Time Frame: day 1 ]
    Volume of local anesthesic needed during bronchoscopy

  3. length of bronchoscopy [ Time Frame: Day 1 ]
    length of bronchoscopy

  4. desaturation episodes [ Time Frame: day 1 ]
    desaturation episodes during bronchoscopy



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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Current and regular smokers needing a bronchoscopy as determined by their own physician
Criteria

Inclusion Criteria:

  • current and regular smoker
  • bronchoscopy under local anesthesia

Exclusion Criteria:

  • patients needing EBUS or fluoroscopy
  • intravenous sedative

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01345383


Locations
Belgium
CHU Saint Pierre
Brussels, Belgium, 1000
Sponsors and Collaborators
Centre Hospitalier Universitaire Saint Pierre
Investigators
Principal Investigator: Isabelle De Meulder, MD Centre Hospitalier Universitaire Saint Pierre

Responsible Party: Marie Bruyneel, Chef de clinique adjoint, Centre Hospitalier Universitaire Saint Pierre
ClinicalTrials.gov Identifier: NCT01345383     History of Changes
Other Study ID Numbers: AK/10-05-3898/38
First Posted: May 2, 2011    Key Record Dates
Last Update Posted: March 10, 2015
Last Verified: March 2015

Keywords provided by Marie Bruyneel, Centre Hospitalier Universitaire Saint Pierre:
smoking
bronchoscopy
cough