Dog Hair Extract Study
|ClinicalTrials.gov Identifier: NCT01343420|
Recruitment Status : Completed
First Posted : April 28, 2011
Last Update Posted : March 29, 2017
Liquid allergen extracts contain proteins, such as (but not limited to) tree, weed, cat, cockroach, and nuts, and are used to identify allergies by observing the body's reaction to the introduction of extract underneath the skin. There are a few dog allergen extracts commercially available in the US for allergy testing; however, none of these products are standardized, meaning they are not required to be the same strength. Because some extracts are not as potent (strong) as others, it's possible that some patients' allergies are misdiagnosed. Typically, the most potent (strong), but safe extract should be used so that allergic patients are correctly diagnosed.
The purpose of this study is to compare the safety and potency of an investigational (not approved for use by the United States Food and Drug Administration [FDA]) dog allergen extract with two commercially available dog extracts, which are of differing potencies.
|Condition or disease||Intervention/treatment|
|Potency of Dog Hair Extract||Biological: Dog Hair Extract, ALK-Abelló, Inc.|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||15 participants|
|Intervention Model:||Single Group Assignment|
|Official Title:||Dog Hair Evaluation Potency by Prick Skin Testing|
|Study Start Date :||November 2010|
|Primary Completion Date :||October 2011|
|Study Completion Date :||October 2011|
|Active Comparator: Dog Hair Extract, ALK-Abelló, Inc.||
Biological: Dog Hair Extract, ALK-Abelló, Inc.
ALK-Abelló dog epithelial 1:10w/v glycerin
- End-point dilution giving a positive prick skin test in dog allergic subjects. [ Time Frame: Study Completion ]The concentration of each allergen extract which produced a 5 mm wheal for each subject will be calculated. From this, the relative potency of each extract will be calculated.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01343420
|United States, Colorado|
|National Jewish Health|
|Denver, Colorado, United States, 80206|
|Principal Investigator:||Harold Nelson, M.D.||National Jewish Health|