Effect of Dietary Sodium Intake on Blood Pressure in Hypertensive Patients in Primary Care
There is strong evidence that our current consumption of salt is the major factor increasing blood pressure (BP). The current salt intake in most countries in the world is 9 to 12 grams per day (g/d), whil the World Health Organization's recommendation is < 5 g/d.
The aims of the present study is to determine if the overconsumption of salt influences the bp in patients with uncontrolled hypertension or frequently elevated bp.
Each study subject will complete questionnaires, and their usual dietary salt intake is estimated from food composition on 3 completed food diaries. This is also compared with a 24-hour urine sample collection.
Based on these results, the study subject receives personal advice to decrease sodium consumption and will change the diet for at least 28 days. During this diet, bp will be measured and food diaries will be completed. After the intervention, a questionnaire and a 24-hour urine sample collection will be collected.
|Study Design:||Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:||Effect of Dietary Sodium Intake on Blood Pressure in Hypertensive Patients in Primary Care|
- Measurement of blood pressure after a 4-week diet, low in sodium. [ Time Frame: after 4 weeks ] [ Designated as safety issue: No ]
- Life style change after a 4-week diet, low in sodium. [ Time Frame: after 4 weeks ] [ Designated as safety issue: No ]
|Study Start Date:||May 2010|
|Study Completion Date:||April 2011|
|Primary Completion Date:||April 2011 (Final data collection date for primary outcome measure)|
Experimental: 4-week diet, low in sodium
The study subjects go on a 4-week diet, low in sodium.
Other: A 4-week diet, low in sodium.
Study subjects receive personal advice to decrease sodium consumption and will change his diet for 28 days.
Follow up is performed by measuring blood pressure, a 24-hour urine sample collection, diaries and questionnaires.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01334138
|Ghent, Belgium, 9000|
|Principal Investigator:||Stefaan Dehenauw, Ph.D, Professor||University Ghent|