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Tinnitus and Arterial Hypertension

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified March 2015 by Faculdade de Medicina de Valenca.
Recruitment status was:  Enrolling by invitation
Federal University of São Paulo
Information provided by (Responsible Party):
Ricardo Rodrigues Figueiredo, Faculdade de Medicina de Valenca Identifier:
First received: April 7, 2011
Last updated: March 4, 2015
Last verified: March 2015
Many authors link tinnitus to arterial hypertension. The aim of this study is to establish a possible relationship between them, analyze the severity of tinnitus related to arterial hypertension and analyze a possible influence of ototoxic drugs used to treat arterial hypertension

Hearing Loss
Arterial Hypertension

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Tinnitus and Arterial There Any Relationship?

Resource links provided by NLM:

Further study details as provided by Faculdade de Medicina de Valenca:

Primary Outcome Measures:
  • Incidence of tinnitus - have tinnitus x don't have tinnitus [ Time Frame: Up to 6 months ]
    The purpose of this study is to compare tinnitus incidence between patients with and without arterial hypertension.

Secondary Outcome Measures:
  • Severity of tinnitus - Tinnitus Handicap Inventory [ Time Frame: Up to 6 months ]
    Severity of tinnitus measured by Tinnitus Handicap Inventory, to evaluate differences between patients with and without arterial hypertension

Estimated Enrollment: 100
Study Start Date: April 2011
Estimated Study Completion Date: October 2015
Estimated Primary Completion Date: April 2015 (Final data collection date for primary outcome measure)
Normal subjects
Arterial hypertension patients

Detailed Description:
Arterial hypertension has been cited as a possible tinnitus etiology. Vascular abnormalities associated with it may account for cochlear and central nervous system. However, a relationship between tinnitus and arterial hypertension has never been established. The aim of this study is to analyze this relationship, comparing groups with and without arterial hypertension and the incidence of tinnitus amongst them. Inclusion and exclusion criteria try to isolate arterial hypertension as the main etiological factor, as much as possible. Presbycusis, noise exposure, metabolical diseases and genetic factors will be ruled out. A comparison will be performed inside the arterial hypertension group between subgroups that use or not ototoxic medications, such as furosemide and beta-blockers

Ages Eligible for Study:   40 Years to 49 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Patients agedd between 40 and 50

Inclusion Criteria:

  • age between 40 and 50
  • arterial hypertension for group 1
  • at least 5 years standing arterial hypertension

Exclusion Criteria:

  • chronic noise exposure
  • metabolic diseases
  • family antecedents of hearing loss (except for presbycusis)
  • pregnant women
  • use of ototoxic drugs (except for anti-hypertensives)
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Please refer to this study by its identifier: NCT01333683

Faculdade de Medicina de Valença
Valença, RJ, Brazil, 27660-000
Sponsors and Collaborators
Faculdade de Medicina de Valenca
Federal University of São Paulo
Principal Investigator: Ricardo R Figueiredo, MD,MSc Otosul, Valença Medical School
  More Information

Responsible Party: Ricardo Rodrigues Figueiredo, M.D, MSc, Faculdade de Medicina de Valenca Identifier: NCT01333683     History of Changes
Other Study ID Numbers: HAS
Study First Received: April 7, 2011
Last Updated: March 4, 2015

Keywords provided by Faculdade de Medicina de Valenca:
hearing loss
arterial hypertension

Additional relevant MeSH terms:
Hearing Loss
Vascular Diseases
Cardiovascular Diseases
Hearing Disorders
Ear Diseases
Otorhinolaryngologic Diseases
Sensation Disorders
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms processed this record on May 25, 2017