We updated the design of this site on September 25th. Learn more.
Show more
ClinicalTrials.gov
ClinicalTrials.gov Menu

Frequency and Origin of Dysnatremias in the Emergency Department

This study has been withdrawn prior to enrollment.
(Job change of responsible investigators)
Sponsor:
ClinicalTrials.gov Identifier:
NCT01326429
First Posted: March 30, 2011
Last Update Posted: July 23, 2015
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborator:
Steering committee of the NCCR
Information provided by:
University Hospital Inselspital, Berne
  Purpose

Hypo- and hypernatremia are the most frequent electrolyte disorders found in hospitalized patients. The increasing use of diuretics and other medications influencing the water and sodium homeostasis potentially lead to a rise in the prevalence of the electrolyte disorders. Only little data is available on the frequency and the mechanisms leading to hypo-/hypernatremia.

Thus, the investigators aim to A.) determine the frequency of hypo- and hypernatremia in the emergency department of a large tertiary university hospital and B.) explore the mechanisms leading to the development of dysnatremias by detailed clinical and laboratory examinations.


Condition
Hyponatremia Hypernatremia

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Frequency and Origin of Dysnatremias in the Emergency Department

Further study details as provided by University Hospital Inselspital, Berne:

Primary Outcome Measures:
  • Frequency of hypo- and hypernatremia in the emergency department [ Time Frame: approx. 6 months ]
    The investigators aim to determine the frequency of hypo- and hypernatremia in the emergency department of a large tertiary university hospital.


Secondary Outcome Measures:
  • Origin of hypo- and hypernatremia in the emergency department [ Time Frame: approx. 6 months ]
    The investigators try to investigate the mechanisms leading to the development of hypo- and hypernatremia in patients admitted to the emergency department.


Biospecimen Retention:   Samples With DNA
whole blood

Enrollment: 0
Study Start Date: October 2011
Study Completion Date: March 2013
Primary Completion Date: March 2013 (Final data collection date for primary outcome measure)
Groups/Cohorts
Hypernatremia
Patients admitted to the emergency department with a serum sodium exceeding 145 mmol/L.
Hyponatremia
Patients admitted to the emergency room with a serum sodium below 135 mmol/L.

  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
All patients admitted to the emergency department of a large tertiary university hospital with a serum sodium below 135 mmol/L (hyponatremia) or exceeding 145 mmol/L.
Criteria

Inclusion Criteria:

  • Serum sodium below 135 mmol/L (i.e. hyponatremia); serum sodium exceeding 145 mmol/L (hypernatremia)

Exclusion Criteria:

  • Patients below age 18 years; patients declining study participation.
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01326429


Sponsors and Collaborators
University Hospital Inselspital, Berne
Steering committee of the NCCR
Investigators
Principal Investigator: Gregor Lindner, M.D. Dept. of Nephrology and Hypertension, Inselspital Bern, University of Bern
Study Chair: Felix J Frey, M.D. Dept. of Nephrology and Hypertension, Inselspital Bern, University of Bern
  More Information

Additional Information:
Responsible Party: Gregor Lindner M.D., Dept. of Nephrology and Hypertension, Inselspital Bern, University of Bern
ClinicalTrials.gov Identifier: NCT01326429     History of Changes
Other Study ID Numbers: KEK 019/11
First Submitted: March 29, 2011
First Posted: March 30, 2011
Last Update Posted: July 23, 2015
Last Verified: July 2015

Keywords provided by University Hospital Inselspital, Berne:
Sodium
Hyponatremia
Hypernatremia
Emergency department

Additional relevant MeSH terms:
Emergencies
Hyponatremia
Hypernatremia
Disease Attributes
Pathologic Processes
Water-Electrolyte Imbalance
Metabolic Diseases


To Top