Retrospective Analysis of Treatment Outcomes in Patients With Bacterial Overgrowth Syndrome Diagnosed by D-Xylose Breath Testing (SIBO)
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|ClinicalTrials.gov Identifier: NCT01324895|
Recruitment Status : Completed
First Posted : March 29, 2011
Last Update Posted : March 26, 2012
The objective of this study is to compare the efficacy of prokinetics versus antibiotics versus a combination of antibiotics plus prokinetics in the eradication of Small-Intestinal Bacterial Over-Growth Syndrome (SIBO) in those with and without a positive D-xylose Breath Test.
Hypothesis: Patients with SIBO treated with a combination of prokinetics and in particular octreotide and antibiotics will have reduced recurrence rates of SIBO than either therapy given alone.
|Condition or disease|
|Small Intestinal Bacterial Overgrowth Syndrome (SIBO) Small Bowel Bacterial Overgrowth Syndrome (SBBOS)|
|Study Type :||Observational|
|Actual Enrollment :||944 participants|
|Observational Model:||Case Control|
|Official Title:||Retrospective Analysis of Treatment Outcomes in Patients With Bacterial Overgrowth Syndrome Diagnosed by D-Xylose Breath Testing|
|Study Start Date :||August 2010|
|Actual Primary Completion Date :||March 2012|
|Actual Study Completion Date :||March 2012|
- clinical response to treatments as measured by changes in patients' GI symptoms, weight and lab data [ Time Frame: A retrospective chart review of up to 8 clinical visits between January 2000 and September 2010 will be conducted on all patients who have had a D-Xylose Breath Test at the Shands Motility Laboratory at the University of Florida during this time period ]Overall clinical response to each treatment (antibiotic, pro-kinetic, or both) and any symptoms reported in up to 8 separate clinical visits in the follow-up of these patients during the above mentioned time period will be analyzed and reviewed retrospectively using the patients' charts.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01324895
|United States, Florida|
|University of Florida|
|Gainesville, Florida, United States, 32610|
|Principal Investigator:||Baharak Moshiree, MD, MS||University of Florida|