Laparoscopic Nissen Versus Toupet Fundoplication: Objective and Subjective Results of a Prospective Randomized Trial

This study has been completed.
Information provided by:
General Public Hospital Zell am See Identifier:
First received: March 21, 2011
Last updated: March 22, 2011
Last verified: March 2011
The aim of this study is to compare subjective and objective outcome and surgical "side effects" of Nissen and Toupet fundoplication performed in a single institution by only two surgeons and to compare pre and postoperative findings to healthy individuals.

Condition Intervention
Gastroesophageal Reflux Disease
Laparoscopic Antireflux Surgery
Procedure: laparoscopic anti-reflux surgery

Study Type: Interventional

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Further study details as provided by General Public Hospital Zell am See:

Arms Assigned Interventions
Active Comparator: Nissen fundoplication Procedure: laparoscopic anti-reflux surgery
Active Comparator: Toupet fundoplication Procedure: laparoscopic anti-reflux surgery


Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both

Inclusion Criteria:

  • Clinical diagnosis of gastroesophageal reflux disease
  • Long history of GERD symptoms
  • Persistent or recurrent symptoms despite optimal medical treatment
  • Persistent or recurrent complications of GERD
  • Reduced quality of life owing to increasing esophageal exposure to gastric juice
  • Pathological values in the preoperative evaluated functional parameters

Exclusion Criteria:

  • Previous esophageal or gastric surgery
  • Poor physical status (American Society of Anesthesiologists (ASA) scores III and IV)
  • Pregnancy
  Contacts and Locations
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Please refer to this study by its identifier: NCT01321294

General Public Hospital Zell am See
Zell am See, Salzburg, Austria, 5700
Sponsors and Collaborators
General Public Hospital Zell am See
  More Information

No publications provided by General Public Hospital Zell am See

Additional publications automatically indexed to this study by Identifier (NCT Number): Identifier: NCT01321294     History of Changes
Other Study ID Numbers: Zell01
Study First Received: March 21, 2011
Last Updated: March 22, 2011
Health Authority: Austria: Institutional Review Board

Additional relevant MeSH terms:
Gastroesophageal Reflux
Deglutition Disorders
Digestive System Diseases
Esophageal Diseases
Esophageal Motility Disorders
Gastrointestinal Diseases processed this record on December 01, 2015