Laparoscopic Nissen Versus Toupet Fundoplication: Objective and Subjective Results of a Prospective Randomized Trial
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The aim of this study is to compare subjective and objective outcome and surgical "side effects" of Nissen and Toupet fundoplication performed in a single institution by only two surgeons and to compare pre and postoperative findings to healthy individuals.
Condition or disease
Gastroesophageal Reflux DiseaseLaparoscopic Antireflux Surgery
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Ages Eligible for Study:
18 Years and older (Adult, Senior)
Sexes Eligible for Study:
Clinical diagnosis of gastroesophageal reflux disease
Long history of GERD symptoms
Persistent or recurrent symptoms despite optimal medical treatment
Persistent or recurrent complications of GERD
Reduced quality of life owing to increasing esophageal exposure to gastric juice
Pathological values in the preoperative evaluated functional parameters
Previous esophageal or gastric surgery
Poor physical status (American Society of Anesthesiologists (ASA) scores III and IV)