PET-CT in Diagnosis of Pancreatic Cystic Neoplasms
|ClinicalTrials.gov Identifier: NCT01317836|
Recruitment Status : Completed
First Posted : March 17, 2011
Last Update Posted : February 17, 2014
|Condition or disease|
|Neoplasms Pancreatic Cancer|
Today, in clinical practice the diagnosis pancreatic cystic neoplasms are based on MDCT, MRI and ERCP followed by surgical exploration. The information gained by conventional imaging modalities is restricted to the morphological details, which usually is insufficient for the definitive staging of the pancreatic cystic neoplasms. Based on these previous studies, it seems that PET especially combined with CT modality could improve the diagnostic accuracy of the pancreatic cystic lesions.
So far, there are only few cases published concerning the role of 18F-FDG-PET-CT in the differential diagnosis of cystic pancreatic lesions. Therefore, more studies are needed to determine the role of combined 18F-FDG-PET-CT in the diagnosis of pancreatic cystic lesions.
The aim of the current project is to evaluate the possibility to enhance the diagnostic accuracy by using the combined 18F-FDG-PET-CT imaging in patients with pancreatic cystic neoplasms by combining PET-CT with MRI and MDCT.
The study consists of 20-30 patients with pancreatic cystic neoplasms. The patients enrolled in the study will be imaged by MDCT, MRI combined with magnetic resonance cholangiopancreatography (MRCP), endoscopic retrograde cholangiopancreatography (ERCP) and 18F-FDG-PET-CT followed by surgery or follow-up. The data will be collected between 2011 and 2013.
|Study Type :||Observational|
|Actual Enrollment :||31 participants|
|Official Title:||PET-CT in Diagnosis of Pancreatic Cystic Neoplasms|
|Study Start Date :||March 2011|
|Primary Completion Date :||December 2013|
|Study Completion Date :||January 2014|
|Patients having pancreatic cystic lesion|
- Predictive Value of PET/CT imaging for Identifying Malignant and Benign Pancreatic Cystic Lesions [ Time Frame: 1 mo ]To determine sensitivities, specificities, accuracy and positive/negative predictive values of PET/CT imaging for differentiating malignant and benign cystic lesions in patients who are to undergo surgical resection.
- To compare PET/CT to ERCP, MDCT and MRI-MRCP [ Time Frame: 1 mo ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01317836
|Turku University Hospital|
|Turku, Finland, 20521|
|Principal Investigator:||Saila Kauhanen, PhD||Turku University Hospital|