Use of Granulocyte Colony-stimulating Factor for the Treatment of Recurrent Implantation Failure in IVF Patients
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ClinicalTrials.gov Identifier: NCT01315470
Verified March 2011 by Hadassah Medical Organization. Recruitment status was: Not yet recruiting
The investigators use granulocyte colony-stimulating factor (GCSF) for the treatment of recurrent implantation failure in IVF patient with cause unknown or due to thin endometrium. Several studies showed that GCSF improves embryo development and implantation and increase pregnancy rate.
Condition or disease
Drug: neupogen administration for women with recurrent IVF failure
The investigators use granulocyte colony-stimulating factor (GCSF) for the treatment of repeated implantation failure (5 cycles) in IVF patient with cause unknown or due to thin endometrium. we intend to treat with GCSF during the IVF cycle if thin endometrium (<6 mm) is the cause for the treatment failure, and during the implantation window if cause unknown.
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Ages Eligible for Study:
20 Years to 45 Years (Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
women after 5 failures in IVF cycles with cause unknown.
women after 5 failures in IVF due to thin endometrium (<6 mm) and unresponsive to estrogen supplements.