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Use of Autobiographical and Interest Assessment for a Better Stimulation of Patients in Nursing Home

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified January 2011 by Association Recherche Méthodologie Evaluation Psychiatrique.
Recruitment status was:  Recruiting
Information provided by:
Association Recherche Méthodologie Evaluation Psychiatrique Identifier:
First received: March 11, 2011
Last updated: April 28, 2011
Last verified: January 2011
The purpose is to evaluate patients' interests (patients in nursing home). Moreover the study aims to evaluate whether an activity for which the patient is interested in, allows a better involvement and stimulation.

Condition Intervention
Alzheimer's Disease
Behavioral: Stimulation group

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: Open Label
Official Title: Use of Autobiographical and Interest Assessment for a Better Stimulation of Patients in Nursing Home

Resource links provided by NLM:

Further study details as provided by Association Recherche Méthodologie Evaluation Psychiatrique:

Primary Outcome Measures:
  • The primary outcome is the engagement duration for an activity, measured by the OME (Observational Measurement of Engagement) scale. [ Time Frame: 10 times during two weeks ]

    First, a cognitive and behaviour assessment (specially autobiographical memory) is performed to patients.

    Then, the patient is proposed to do 5 activities. 4 of them correpond to activities for which he is interested in (depending on the assessment results). The therapist assesses if the patient is stimulated, by measuring the time for which he is involved in doing the activity (with OME Scale)

Estimated Enrollment: 48
Study Start Date: March 2011
Estimated Study Completion Date: June 2012
Estimated Primary Completion Date: September 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Intervention group Behavioral: Stimulation group

Patients living in nursing home can be enrolled in the study by giving their verbal consent. The trial lasts two weeks for each patients and it will be performed in three parts :

  • a cognitive and behaviour assessment : MMSE, BREF, NPI, IA
  • an interest questionnaire for patients. It contains 40 questions about activities.
  • the intervention : patients will be propose 5 activities. 4 of them are activities that patients are interested in. Each activity have to last 15 minutes and the stimulation is measured by a scale named "Observational Measurement of Engagement ".
Other Names:
  • interest
  • autobiography

Detailed Description:

Context :

Behavioral and Psychological Symptoms of Dementia (BPSD) arouse researchers' interest because they are frequent manifestations responsible for a large share of the suffering of patients and caregivers. Apathy is the most frequent of them.

Systematic literature reviews on non-pharmacological treatment for BPSD indicates that some technique and more particularly residential care staff training program appear to have promising results, even if the level of evidence of efficacy remains moderate partly because of the paucity of scientific quality research in this area.

The most of them comes from Anglo-Saxon country. In France, the TNM en EHPAD study demonstrated the staff training program efficacy regarding to the management of behavioral positive symptoms such as agitation or aggressiveness compared to a control group

Aims of the study :

The aims of the study is to evaluate the short and medium term effectiveness of staff training program to manage and stimulate patients with a diagnosis of Alzheimer's disease or associated disorders and presenting BPSD of the apathy type and living in nursing homes.

Description :

A Randomized controlled trial (randomization by nursing home) presents as a routine clinical procedure according to the French regulation. Raters and our statistician are unaware and blind to the randomization. The trial takes place in 4 nursing homes.

To be included, patients are older than 65 years with a diagnosis of Alzheimer's disease or associated disorder and present the diagnostic criteria of apathy, within a moderate to severe stage of the disease.

Data are collected at baseline, month 1 and at month 4, namely 3 months after the end of the training programme thanks to the Apathy Inventory Clinician version (AI-C), the Neuropsychiatric Inventory for the staff members (NPI-ES), the AD QOL, an Observation Scale and a qualitative analysis of the official caregiver's knowledge and perception about BPSD especially apathy and their expectations concerning the training program.


Ages Eligible for Study:   60 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Diagnosis of Alzheimer's disease
  • MMSE score between 12 and 24
  • Patient involved in organized activities in nursing home

Exclusion Criteria:


  • Who are not able to understand and answer to questions for the study
  • < 60 years of age
  • Who are not able to sit
  • Aphasic
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01314131

Contact: Philippe ROBERT, PhD +33492034770

Centre Mémoire de Ressources et de Recherche Recruiting
Nice, France, 06000
Contact: Philippe ROBERT, PhD    +33492034770   
Principal Investigator: Philippe ROBERT, PhD         
Sponsors and Collaborators
Association Recherche Méthodologie Evaluation Psychiatrique
Principal Investigator: Philippe ROBERT, PhD Centre Mémoire de Ressources et de Recherche
  More Information

Responsible Party: Pr ROBERT Philippe, Centre Mémoire de Ressources et de Recherche Identifier: NCT01314131     History of Changes
Other Study ID Numbers: ARMEP-01
Study First Received: March 11, 2011
Last Updated: April 28, 2011

Additional relevant MeSH terms:
Alzheimer Disease
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Neurodegenerative Diseases
Neurocognitive Disorders
Mental Disorders processed this record on May 22, 2017