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LUPS-Lipids and Glucose Under Prospective Surveillance (LUPS)

This study is ongoing, but not recruiting participants.
City of Hamburg
Universitätsklinikum Hamburg-Eppendorf
Information provided by:
Asklepios proresearch Identifier:
First received: March 10, 2011
Last updated: NA
Last verified: March 2011
History: No changes posted
Prospective, non-randomized cohort study to analyse genetic variations, dietary patterns, perceived stress and anxiety and early changes in lipid metabolism leading to the metabolic syndrome and type 2 diabetes

Metabolic Syndrome, Syndrome X, MetS, Diabetes Mellitus, Non-Insulin-Dependent

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Lipids and Glucose Under Prospective Surveillance

Resource links provided by NLM:

Further study details as provided by Asklepios proresearch:

Primary Outcome Measures:
  • Metabolic Syndrome, Type 2 Diabetes [ Time Frame: 10 years ]
    assessing risk factors, e.g. HDL, BMI, Blood Pressure, FPG

Enrollment: 1962
Study Start Date: November 2008
Estimated Primary Completion Date: May 2020 (Final data collection date for primary outcome measure)
Detailed Description:
The LUPS-study is a collaboration between Asklepios Clinics Hamburg GmbH and University Clinic Hamburg Eppendorf, Germany. This study is assessing a multitude of serum biomarkers, anthropometrics, dietary habits, physical activity, perceived stress along with genetic information from "healthy workers" (25-60years) to better understand phenotype-genotype associations leading to MetS and type 2 diabetes.

Ages Eligible for Study:   25 Years to 60 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
so-called "Healthy-Workers", aged 25-60years, of Lufthansa-Technik, Hamburg, Germany, who voluntarily aggreed to participate in the study.

Inclusion Criteria:

  • 25-60 years men and women willing to give consent

Exclusion Criteria:

  • diabetes (type 1 or 2)
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01313156

Asklepios Klinik St.Georg
Hamburg, Germany, 20099
Universitätsklinikum Eppendorf
Hamburg, Germany, 20246
Sponsors and Collaborators
Asklepios proresearch
City of Hamburg
Universitätsklinikum Hamburg-Eppendorf
Principal Investigator: Dirk Mueller-Wieland, Prof., MD Asklepios Klinik St.Georg, Hamburg, Germany
Principal Investigator: Karl Wegscheider, Prof., PHD Universitätsklinikum Hamburg Eppendorf, Germany
  More Information

Responsible Party: 1.Prof. Mueller-Wieland; 2.Prof.Wegscheider, 1.Asklepios Klinik St.Georg, I.Med.; 2. Universitätsklinikum HH-Eppendorf, Abtlg.f. Epidemiologie Identifier: NCT01313156     History of Changes
Other Study ID Numbers: AKS#1833
Study First Received: March 10, 2011
Last Updated: March 10, 2011

Keywords provided by Asklepios proresearch:
Metabolic Syndrome, Syndrome X, MetS,
Type 2 Diabetes

Additional relevant MeSH terms:
Diabetes Mellitus
Metabolic Syndrome X
Diabetes Mellitus, Type 2
Glucose Metabolism Disorders
Metabolic Diseases
Insulin Resistance
Pathologic Processes
Endocrine System Diseases
Hyperinsulinism processed this record on September 19, 2017