We updated the design of this site on September 25th. Learn more.
Show more
ClinicalTrials.gov
ClinicalTrials.gov Menu

Feeling of Being in Control of One's Own Action

This study is currently recruiting participants.
Verified September 2016 by University Hospital, Strasbourg, France
Sponsor:
ClinicalTrials.gov Identifier:
NCT01312649
First Posted: March 11, 2011
Last Update Posted: September 16, 2016
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
Information provided by (Responsible Party):
University Hospital, Strasbourg, France
  Purpose
The investigators aim is to understand the cognitive mechanisms that contribute to the emergence of delusions of control (the belief that one's own actions or thoughts are controlled by an external force). These symptoms are mainly encountered in patients with schizophrenia, and the investigators will distinguish patients with schizophrenia with or without this symptom together with patients with bipolar disorder. Based on the investigators previous studies, this project will help to determine the role of two elementary mechanisms in the ability to feel in control of voluntary actions: (1) the processing of the sensory consequences of action, and (2) the ability to build mental representations for sequenced actions.

Condition Intervention
Schizophrenia Bipolar Disorders Behavioral: Experimental psychology methods (computer tests)

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Outcomes Assessor)
Primary Purpose: Basic Science
Official Title: Feeling of Being in Control of One's Own Action: Which Mechanisms in Healthy Volunteers and in Mental Diseases

Resource links provided by NLM:


Further study details as provided by University Hospital, Strasbourg, France:

Estimated Enrollment: 370
Study Start Date: April 2011
Estimated Study Completion Date: December 2017
Estimated Primary Completion Date: December 2017 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Arm 1
Healthy volunteers
Behavioral: Experimental psychology methods (computer tests)
Experimental: Arm 2
Schizophrenia with history of delusions of control
Behavioral: Experimental psychology methods (computer tests)
Experimental: Arm 3
Schizophrenia without history of delusions of control
Behavioral: Experimental psychology methods (computer tests)
Experimental: Arm 4
Bipolar disorders
Behavioral: Experimental psychology methods (computer tests)
Active Comparator: Arm 5
Matched healthy controls
Behavioral: Experimental psychology methods (computer tests)

  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years to 55 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Patients with schizophrenia or bipolar disorders (criteria DSM IV) or healthy controls matched with patients on age, sex and education level
  • 18-55 years old

Exclusion Criteria:

  • Past history affecting CNS
  • Invalidating sensory disorders
  • Intake of psychotropic drugs, except for patients
  • Intake of benzodiazepines
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01312649


Contacts
Contact: Anne Giersch 3.33.88.11.64.71 giersch@alsace.u-strasbg.fr

Locations
France
Pôle de Psychiatrie - Hôpital civil Recruiting
Strasbourg, France
Contact: Anne GIERSCH, MD    3.33.88.11.64.71    giersch@alsace.u-strasbg.fr   
Sub-Investigator: Gilles BERTSCHY, MD         
Sub-Investigator: Laurence LALANNE, MD         
Sub-Investigator: Sebastien WEIBEL, MD         
Principal Investigator: Anne GIERSCH, MD         
Sponsors and Collaborators
University Hospital, Strasbourg, France
Investigators
Study Director: Anne GIERSCH, MD Hôpitaux Universitaires de Strasbourg
  More Information

Responsible Party: University Hospital, Strasbourg, France
ClinicalTrials.gov Identifier: NCT01312649     History of Changes
Other Study ID Numbers: 4880
First Submitted: March 1, 2011
First Posted: March 11, 2011
Last Update Posted: September 16, 2016
Last Verified: September 2016

Additional relevant MeSH terms:
Schizophrenia
Bipolar Disorder
Schizophrenia Spectrum and Other Psychotic Disorders
Mental Disorders
Bipolar and Related Disorders


To Top