Orange Juice Consumption and Cognitive Function (OJOC)
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|ClinicalTrials.gov Identifier: NCT01312610|
Recruitment Status : Completed
First Posted : March 10, 2011
Last Update Posted : November 23, 2011
|Condition or disease||Intervention/treatment||Phase|
|Nerve Degeneration||Dietary Supplement: High flavanone orange juice Dietary Supplement: Control orange juice||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||40 participants|
|Intervention Model:||Crossover Assignment|
|Primary Purpose:||Basic Science|
|Official Title:||Effect of Chronic Orange Juice Consumption on Cognitive Function in Healthy Older Adults|
|Study Start Date :||September 2010|
|Actual Primary Completion Date :||August 2011|
|Actual Study Completion Date :||September 2011|
|Experimental: High flavonone orange juice drink||
Dietary Supplement: High flavanone orange juice
High flavonone orange juice drink.
Other Name: Frozen Orange Juice; Department of Citrus, Florida, USA.
Placebo Comparator: Control orange juice drink
Juice drink matched for sugar content
Dietary Supplement: Control orange juice
Orange beverage, low flavanone content, matched for total carbohydrate content, individual sugar profile, vitamin C
- Executive function - Attention [ Time Frame: change in attention from baseline and 8 weeks ]Assessment by human cognitive test battery delivered by computer and human operator. Assessments will be carried out at baseline and at the end of each intervention arm.
- Plasma flavanones [ Time Frame: change from baseline to 8 weeks ]By High performance liquid chromatography
- Blood pressure [ Time Frame: change from baseline to 8 weeks ]Blood pressure measurement
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01312610
|University of Reading|
|Reading, Berkshire, United Kingdom, RG6 6AH.|
|Principal Investigator:||Jeremy PE Spencer, PhD||University of Reading|
|Principal Investigator:||Laurie T. Butler, PhD||University of Reading|