Unknown Glucose Metabolism Disorders In Patients With Coronary Artery Disease
|ClinicalTrials.gov Identifier: NCT01310556|
Recruitment Status : Completed
First Posted : March 8, 2011
Last Update Posted : June 21, 2011
|Condition or disease||Intervention/treatment|
|Diabetes Mellitus||Other: ogtt for patients with coronary artery disease|
Context: There are more than 220 million people diagnosed with diabetes mellitus (DM) in the world. DM is a serious risk factor for coronary artery disease (CAD). This study aimed to examine the prevalence of glucose metabolism disorders (GMD) in te patients with coronary artery disease and the relationship between different GMDs and CAD.
Settings: 230 patients with coronary artery disease and without any known GMDs were included the study. Coronary angiography was used to diagnose CAD. Patients were administered the 75 g Oral Glucose Tolerance Test (OGTT).
|Study Type :||Observational|
|Actual Enrollment :||230 participants|
|Observational Model:||Case Control|
|Official Title:||The Relationship Between Previously Unknown Glucose Metabolism Disorders and Coronary Artery Disease in Patients Suffering From Coronary Artery Disease|
|Study Start Date :||June 2009|
|Primary Completion Date :||June 2010|
|Study Completion Date :||June 2010|
coronary artery disease
patients with coronary artery disease
Other: ogtt for patients with coronary artery disease
75 g OGTT
Other Name: no name
- Frequency of unknown glucose metabolism disorders in patients with coronary artery disease [ Time Frame: 1 year ]Results: While GMDs were detected in 58.26% (n=134 patients) of CAD patients, 41.74% of them (n=96 patients) were found to have normal glucose metabolism.
- Fasting and 120 minute glucose levels have relation with vessels' stenosis. [ Time Frame: 1 year ]Fasting glucose level was found to have a significant correlation with the total number of stenotic coronary vessels (p=0.0001) and the stenosis rate of all vessels . OGTT 120-minute glucose levels were found to have a significant correlation with the total number of stenotic coronary vessels and the stenosis rate of vessels with the exception of LAD.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01310556
|Gulhane School of Medicine|
|Ankara, Turkey, 06100|
|Study Director:||Aydogan Aydogdu, MD||Gulhane School of Medicine Ankara/Turkey|