Circadian Rhythm of Blood Lactate

This study has been completed.
State University of New York - Downstate Medical Center
Information provided by (Responsible Party):
Axel Schlitt, Martin-Luther-Universität Halle-Wittenberg Identifier:
First received: February 24, 2011
Last updated: May 1, 2012
Last verified: May 2012
To elucidate whether blood lactate, lipid transfer proteins and PPARs/CLOCK/Bal1 have a circadian rhythm

Condition Intervention
Other: Blood Sampling

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Circadian Rhythm of Blood Lactate, Lipid Transferproteins and Genetic Markers (PPARs, CLOCK, Bmal1)

Resource links provided by NLM:

Further study details as provided by Martin-Luther-Universität Halle-Wittenberg:

Primary Outcome Measures:
  • Circadian rhythm of blood lactate [ Time Frame: 5 months ] [ Designated as safety issue: No ]
    Blood samples

Secondary Outcome Measures:
  • Circadian rhythm of Lipid transfer proteins [ Time Frame: 5 months ] [ Designated as safety issue: No ]

  • Circadian rhythm of PPARs, CLOCK and Bal1 [ Time Frame: 5 months ] [ Designated as safety issue: No ]

Enrollment: 30
Study Start Date: February 2011
Study Completion Date: May 2012
Primary Completion Date: December 2011 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Healthy probands
Healthy probands, age between 18 and 40 years
Other: Blood Sampling
Blood Sampling over 24 hours

Detailed Description:
Blood will be drawn fasting and then every hour over a period of 24 hours in 30 healthy probands.

Ages Eligible for Study:   18 Years to 40 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
30 healthy probands

Inclusion Criteria:

  • Age between 18 and 40 years old

Exclusion Criteria:

  • Inability/unwilling to give written informed consent
  • Chronic disease
  Contacts and Locations
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Please refer to this study by its identifier: NCT01303848

University Clinic Halle, Martin Luther-University Halle-Wittenberg
Halle (Saale), Germany, 06120
Sponsors and Collaborators
Martin-Luther-Universität Halle-Wittenberg
State University of New York - Downstate Medical Center
Principal Investigator: Axel Schlitt, MD Department of Medicine III, University Clinic Halle, Martin Luther-University Halle-Wittenberg
  More Information

No publications provided

Responsible Party: Axel Schlitt, PD Dr. med. habil., Martin-Luther-Universität Halle-Wittenberg Identifier: NCT01303848     History of Changes
Other Study ID Numbers: UKH2011Sport1
Study First Received: February 24, 2011
Last Updated: May 1, 2012
Health Authority: Germany: Federal Institute for Drugs and Medical Devices

Keywords provided by Martin-Luther-Universität Halle-Wittenberg:
Blood lactate
Lipid transfer proteins
Bal1 processed this record on November 25, 2015