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Pulsed Dye Laser for the Psoriatic Nail

This study has been completed.
Information provided by (Responsible Party):
Ying-Yi Chiang, Taipei Medical University WanFang Hospital Identifier:
First received: February 22, 2011
Last updated: December 11, 2014
Last verified: December 2014
The treatment options for nail psoriasis have been limited, and the management of nail psoriasis has been challenging for physicians.To evaluate the effect of pulsed dye laser (PDL) in the treatment of nail psoriasis.

Psoriatic Nail

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Pulsed Dye Laser for the Psoriatic Nail

Further study details as provided by Taipei Medical University WanFang Hospital:

Primary Outcome Measures:
  • NAPSI [ Time Frame: 3rd and 6th months ]
  • global physician assessment [ Time Frame: 3rd and 6th months ]

Enrollment: 25
Study Start Date: January 2011
Study Completion Date: February 2012
Primary Completion Date: February 2012 (Final data collection date for primary outcome measure)
Experimental Group
Control Group

Detailed Description:
Psoriatic nails of patient's right hand were treated using PDL (595 nm) .The pulsed duration is 1.5ms, the beam diameter is 7mm, and the laser energy is 8.0 to 10.0 J/cm2. The treatment course of pulse dye laser is once monthly for 6 months. Psoriatic nails of both hands are treated with Tazarotene cream for 6 months. Clinical efficacy is statistically evaluated according to Nail Psoriasis Severity Index (NAPSI) score differences between right and left hand one month after 3rd and 6th therapy.

Ages Eligible for Study:   16 Years and older   (Child, Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Psoriatic nail patients

Inclusion Criteria:

  • Psoriatic nail refractory to other topical and systemic treatment therapy
  • ≧ 16 years old

Exclusion Criteria:

  • Patient with pregnancy
  • Patient with photo sensitivity
  • Patient with severe wound around finger nails or paronychia
  • Patient with hypersensitivity to Tazarotene cream
  Contacts and Locations
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Please refer to this study by its identifier: NCT01303185

Taipei Medical University - WanFang Hospital
Taipei, Taiwan
Sponsors and Collaborators
Taipei Medical University WanFang Hospital
Principal Investigator: Ying-Yi Chiang Taipei Medical University WanFang Hospital
  More Information

Responsible Party: Ying-Yi Chiang, Attending Physician, Taipei Medical University WanFang Hospital Identifier: NCT01303185     History of Changes
Other Study ID Numbers: 99074
Study First Received: February 22, 2011
Last Updated: December 11, 2014

Keywords provided by Taipei Medical University WanFang Hospital:
Psoriatic Nail
Pulsed dye laser processed this record on April 28, 2017