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Functional and Morphologic Aspects of Intravitreal Triamcinolone for Uveitis-associated Cystoid Macular Edema

This study has been completed.
Information provided by (Responsible Party):
Marion Munk, Medical University of Vienna Identifier:
First received: February 17, 2011
Last updated: December 24, 2011
Last verified: December 2011


To evaluate the effect of intravitreal triamcinolone acetonide (IVTA) on uveitis-associated cystoid macular edema (CME) using high resolution optical coherence tomography (SDOCT) in conjunction with thorough visual function testing.


28 patients with uveitis-associated CME were examined before intravitreal triamcinolone injection (IVTA) (v1) and at day 1 (v2), week 1 (v3) and month 1 (v4) after injection. Retinal anatomy was evaluated using Cirrus HD-OCT (Carl Zeiss Meditec). Visual function testing consisted of assessing ETDRS distance visual acuity (VA), reading acuity and reading speed using a standardized German-language test (Radner Reading charts), contrast sensitivity using Pelli-Robson Contrast Sensitivity charts and fundus-controlled microperimetry using the MP-1 Microperimeter (Nidek). Here we utilized a cartesian grid consisting of a central locus and three concentric box-shaped stimulation areas. The changes of retinal anatomy over time were compared to the respective outcome of visual function.

Uveitis Related Cystoid Macular Edema

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Functional and Morphologic Aspects of Intravitreal Triamcinolone for Uveitis-associated Cystoid Macular Edema

Resource links provided by NLM:

Further study details as provided by Medical University of Vienna:

Enrollment: 30
Study Start Date: June 2009
Study Completion Date: June 2011
Primary Completion Date: June 2011 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
uveitis ambulance patients of the department of ophthalmology, medical university vienna

Inclusion Criteria:

  • intraocular inflammation
  • able to read
  • > 18 years old

Exclusion Criteria:

  • cataract
  • amblyopia
  • dyslexia
  • already applicated intravitreal triamcinolone for current cystoid macular edema
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Please refer to this study by its identifier: NCT01299129

Medical University Vienna
Vienna, Austria, 1090
Sponsors and Collaborators
Medical University of Vienna
  More Information

Responsible Party: Marion Munk, Dr. med. univ, Medical University of Vienna Identifier: NCT01299129     History of Changes
Other Study ID Numbers: 070/2009
Study First Received: February 17, 2011
Last Updated: December 24, 2011

Keywords provided by Medical University of Vienna:
Cystoid macular edema
functional visual acuity
intravitreal triamcinolone

Additional relevant MeSH terms:
Macular Edema
Signs and Symptoms
Macular Degeneration
Retinal Degeneration
Retinal Diseases
Eye Diseases
Uveal Diseases
Triamcinolone hexacetonide
Triamcinolone Acetonide
Triamcinolone diacetate
Anti-Inflammatory Agents
Hormones, Hormone Substitutes, and Hormone Antagonists
Physiological Effects of Drugs
Immunosuppressive Agents
Immunologic Factors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action processed this record on April 26, 2017