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Ankle Tracking Training in Stroke

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01298583
Recruitment Status : Completed
First Posted : February 17, 2011
Last Update Posted : November 1, 2019
Information provided by (Responsible Party):
University of Minnesota

Brief Summary:

The purpose of this study is to compare the improvement in ankle control and brain activation in subjects with stroke resulting from two different forms of telerehabilitation: tracking training, emphasizing accurate movements, versus movement training, involving simple movements.


  1. The Track group will show greater improvement in ankle range of motion compared to the Move group.
  2. The Track group will show greater improvement in ankle tracking accuracy and greater changes in fMRI (increase in relative volume of activation for ipsilesional sensorimotor cortex, increase in laterality index, and decrease in blood-oxygen-level-dependent (BOLD) signal intensity index) compared to Move group.
  3. The Track group will show greater improvement in tracking accuracy at an untrained joint (knee) compared to the Move group.
  4. The Track group will show greater improvement in standing balance.
  5. The Track group will show greater improvement in walking speed and ankle dorsiflexion during gait compared to the Move group.

Condition or disease Intervention/treatment Phase
Stroke Behavioral: ankle tracking training Phase 1

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 16 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Participant)
Primary Purpose: Treatment
Official Title: Ankle Tracking Training in Stroke
Study Start Date : January 2007
Actual Primary Completion Date : January 2008
Actual Study Completion Date : December 2010

Arm Intervention/treatment
Experimental: ankle tracking
subjects track a target with ankle movement
Behavioral: ankle tracking training
one group will use the ankle for tracking, the other group will use the ankle for simple movement

No Intervention: ankle movement

Primary Outcome Measures :
  1. ankle range of motion [ Time Frame: Measurement at pretest, posttest and followup ]

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 85 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  1. Single stroke with an ischemic infarct.
  2. Between 18 and 85 years of age.
  3. Time since stroke onset must be >6 months.
  4. Cannot be receiving any rehabilitation therapy.
  5. Impaired ankle dorsiflexion/plantarflexion but at least 10 degrees of active motion.
  6. Cognition level must be at least 24 out of 30 on the Mini-Mental Examination 7. Able to ambulate at least 100 feet independently. training.

Exclusion Criteria:

  1. Cannot have any neuromuscular disorder other than stroke that impairs ankle motion.
  2. Cannot have an executive function score on Stroop Interference Test of <37.
  3. Cannot have a score on the Beck Depression Inventory of >10.
  4. Cannot have ataxia, apraxia, receptive aphasia, hemi-neglect, or severe visual field cut .
  5. Cannot be pregnant nor have indwelling metal or medical devices incompatible with fMRI.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01298583

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United States, Minnesota
University of Minnesota
Minneapolis, Minnesota, United States, 55455
Sponsors and Collaborators
University of Minnesota
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Principal Investigator: James Carey, PhD University of Minnesota
Publications automatically indexed to this study by Identifier (NCT Number):
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Responsible Party: University of Minnesota Identifier: NCT01298583    
Other Study ID Numbers: 0508M72871
First Posted: February 17, 2011    Key Record Dates
Last Update Posted: November 1, 2019
Last Verified: October 2019
Additional relevant MeSH terms:
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Cerebrovascular Disorders
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Vascular Diseases
Cardiovascular Diseases