Evaluation of Neuroprotective Effect of Minocycline (minocyclin &RD)
|ClinicalTrials.gov Identifier: NCT01297816|
Recruitment Status : Unknown
Verified December 2010 by Shahid Beheshti University of Medical Sciences.
Recruitment status was: Recruiting
First Posted : February 17, 2011
Last Update Posted : February 17, 2011
This process appears as a incredible and progressive event that will not stop till reattachment of RPE and neurosensory retina happened .
Process of degeneration begins from first hours of RD (Retinal Detachment) establishment Neuroprotection of photoreceptor following RD is a novel and debatable discussion encountered in recent years .
How to stop this phenomena and neuroprotective agent role in this issue are a new interest of researcher.
In the study the investigators are planning to perform a clinical trial to demonstrate the minocycline neuroprotective effect in a double blind design as this impact has been implicated previously in a animal study
|Condition or disease||Intervention/treatment||Phase|
|Retinal Detachment||Drug: placebo Drug: Minocycline||Phase 2|
|Study Type :||Interventional (Clinical Trial)|
|Intervention Model:||Single Group Assignment|
|Masking:||Double (Participant, Investigator)|
|Official Title:||Evaluation of Minocycline Neuro Protective Role in Retinal Detachment Surgery|
|Study Start Date :||December 2010|
|Estimated Primary Completion Date :||December 2010|
|Estimated Study Completion Date :||April 2011|
Placebo Comparator: placebo
100mg,BD, fo three month
|Placebo Comparator: minocyclin||
- BCVA [ Time Frame: changes of BCVA in 3 month ]outcome method of measurement: Snellen chart
- finding of ERG changes [ Time Frame: 3 months ]outcome method of measurement: ERG( testes)
- finding of OCT changes [ Time Frame: 3 months ]outcome method of measurement: OCT
- finding of FAF changes [ Time Frame: 3 months ]outcome method of measurement: FAF( testes)
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01297816
|Iran, Islamic Republic of|
|Labbafinejad medical center||Recruiting|
|Tehran, Iran, Islamic Republic of|
|Contact: Mohsen Azarmina, Associate Professor 00982122585952 firstname.lastname@example.org|
|Principal Investigator: Mohsen Azarmina, Associate Professor|