Leptin Signaling in Lean and Obese Humans (Leptin signali)
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ClinicalTrials.gov Identifier: NCT01297426 |
Recruitment Status
:
Withdrawn
(funding expired)
First Posted
: February 16, 2011
Last Update Posted
: December 24, 2015
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Condition or disease |
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Obesity |
Study Type : | Observational |
Actual Enrollment : | 0 participants |
Observational Model: | Case Control |
Time Perspective: | Cross-Sectional |
Official Title: | Leptin Signaling in Humans |
Study Start Date : | April 2011 |
Actual Primary Completion Date : | June 2015 |
Actual Study Completion Date : | June 2015 |
Group/Cohort |
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Group 1
Lean and obese, diabetic and non diabetics
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- Westerns / activation of signaling pathways (uo to two hours after treatment) [ Time Frame: 04/01/2016 ]

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Ages Eligible for Study: | 18 Years to 65 Years (Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Yes |
Sampling Method: | Non-Probability Sample |
Inclusion Criteria:
- men and women
- ages 18 to 65
- BMI ranges between 20 and 45 kg/m2
Exclusion Criteria:
- subjects requiring special diets
- history of illness other than obesity of diabetes
- taking medications known to influence glucose metabolism
- subjects with history of anaphylactic reaction or hypersensitivity to e. coli derived proteins or anesthetic agents
- women who are breastfeeding, pregnant or wanting to become pregnant
- subjects with bleeding dyscrasia or poor wound healing

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01297426
United States, Massachusetts | |
VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA | |
Boston, Massachusetts, United States, 02130 |
Principal Investigator: | Christos Mantzoros, MD DSc | VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA |
Responsible Party: | VA Office of Research and Development |
ClinicalTrials.gov Identifier: | NCT01297426 History of Changes |
Other Study ID Numbers: |
ENDA-013-10F |
First Posted: | February 16, 2011 Key Record Dates |
Last Update Posted: | December 24, 2015 |
Last Verified: | December 2015 |