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Morphological, Structural and Functional Neural Substrates of Quality of Life in Schizophrenia

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ClinicalTrials.gov Identifier: NCT01295411
Recruitment Status : Unknown
Verified April 2015 by Assistance Publique Hopitaux De Marseille.
Recruitment status was:  Active, not recruiting
First Posted : February 14, 2011
Last Update Posted : April 28, 2015
Sponsor:
Information provided by (Responsible Party):

Study Description
Brief Summary:
The aim of the investigators analysis is to identify the neural correlates of quality of life scores in schizophrenia. For this, the investigators will constitute group of patients according to their quality of life scores and the investigators will analyze their differences in patterns of brain structures and activations.

Condition or disease Intervention/treatment
Schizophrenia Device: Magnetic Resonance Imaging Other: EVALUATION NEUROPSYCHOLOGICAL

Study Design

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 100 participants
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Official Title: Morphological, Structural and Functional Neural Substrates of Quality of Life in Schizophrenia
Study Start Date : January 2011
Primary Completion Date : January 2015
Estimated Study Completion Date : September 2015

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Schizophrenia
U.S. FDA Resources

Arms and Interventions

Arm Intervention/treatment
schizophrenia PATIENTS Device: Magnetic Resonance Imaging Other: EVALUATION NEUROPSYCHOLOGICAL


Outcome Measures

Primary Outcome Measures :
  1. to study the relationships between quality of life and the morphologic, structural and functional substrates in schizophrenia [ Time Frame: 36 months ]

Secondary Outcome Measures :
  1. to determine whether quality of life is correlated with brain modifications using functional Magnetic Resonance Imaging [ Time Frame: 36 months ]

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 40 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • diagnosis of schizophrenia according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) criteria (American Psychiatric Association(APA), 1994),
  • age over 18 years,
  • informed consent to participate in the studies
  • French as native language

Exclusion Criteria:

  • diagnosis other than schizophrenia on Axis I of DSM-IV,
  • decompensated organic disease and mental retardation
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01295411


Locations
France
Assistance Publique Hopitaux de Marseille
Marseille, France, 13354
Sponsors and Collaborators
Assistance Publique Hopitaux De Marseille
Investigators
Study Director: BERNARD BELAIGUES Assistance Publique hôpitaux de Marseille