Androgenetic Alopecia in Fabry Disease
|Study Design:||Observational Model: Cohort
Time Perspective: Cross-Sectional
|Official Title:||Androgenetic Alopecia in Fabry Disease|
- No and frontal only androgenetic alopecia [ Time Frame: 1 Year ]No and frontal only androgenetic alopecia opposed to vertex only and frontal and vertex androgenetic alopecia.
- Vertex only and frontal and vertex androgenetic alopecia. [ Time Frame: 1 Year ]
|Study Start Date:||December 2010|
|Study Completion Date:||October 2015|
|Primary Completion Date:||October 2015 (Final data collection date for primary outcome measure)|
|Patients with the classic form|
|Fabry disease and healthy controls|
Objectives: To test the hypothesis that adult males with classic form of Fabry disease have a significantly lower incidence of androgenic alopecia than matched controls.
Study Population: 120 patients aged 20-64 with Fabry disease that have GLA mutations or alpha-galactosidase A activity associated with no residual enzyme activity and non-Fabry male controls of the same age range and the same number of non-Fabry controls.
Design: This is a cross-sectional study comparing the prevalence of androgenic alopecia in two groups of subjects.
Outcome Measures: The levels of the outcome will be no androgenic alopecia and frontal only androgenetic alopecia opposed to vertex only and frontal and vertex androgenetic alopecia.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01295008
|United States, Texas|
|Baylor University Medical Center|
|Dallas, Texas, United States, 75246|
|Principal Investigator:||Raphael Schiffmann, MD||Baylor Research Institute|