Effect of Short-term Chinese Tea-flavor Liquor Consumption (ESTCTFLC)
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|ClinicalTrials.gov Identifier: NCT01294995|
Recruitment Status : Completed
First Posted : February 14, 2011
Last Update Posted : February 14, 2011
Human studies of Chinese liquor are sparse. The investigators hypothesize that short-term Chinese Tea-flavor liquor (TFL) consumption may be beneficial to inflammation biomarkers and CVD risk factors. Guizhou Meijiao Liquor (GML) is a traditional Chinese liquor, fermented from sorghum, corn, sticky rice, wheat and rice, while TFL is a novel Chinese liquor fermented from above 5 grains plus green tea.
Forty-five volunteers(23 males, 22 females) were selected to participate a paralleled randomized trial drinking 30 mL two kinds of Chinese liquors: TFL and GML respectively with meal every day for 28 days. Serums of volunteers were collected for analyzing serum lipids, inflammation biomarkers and CVD risk factors.
TFL could significantly decrease systolic blood pressure of males, but increase diastolic blood pressure of females. TFL could also decreased blood lipid of volunteers, especially for females. Both liquor significantly decrease serum uric acid and glucose in males and females. The effect of the two liquors on inflammation biomarkers were complicated and needs further research work.
TFL may possess more beneficial effect on CVD risk factors than GML probably because of the special fermentation products of green tea with other grains.
|Condition or disease||Intervention/treatment||Phase|
|Cardiovascular Diseases||Dietary Supplement: Tea-flavor Liquor Dietary Supplement: Guizhou Meijiao Liquor||Phase 1|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||45 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||Phase 1 Study of Chinese Tea-flavor Liquor|
|Study Start Date :||October 2010|
|Actual Primary Completion Date :||November 2010|
|Actual Study Completion Date :||November 2010|
Experimental: Tea-flavor Liquor, taken with meal
including 12 males and 11 females
Dietary Supplement: Tea-flavor Liquor
30 mL of Tea-flavor Liquor(45% alcohol content)
Placebo Comparator: Guizhou Meijiao Liquor, taken with meal
including 11 males and 11 females
Dietary Supplement: Guizhou Meijiao Liquor
30 mL of Guizhou Meijiao Liquor (45% alcohol content)
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Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01294995
|Department of food science and nutrition|
|Hangzhou, Zhejiang, China, 310029|