Indicators of Operative and Postoperative Complications in Patients Operated for Hip Fracture (IOPC)
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|ClinicalTrials.gov Identifier: NCT01294930|
Recruitment Status : Completed
First Posted : February 14, 2011
Last Update Posted : February 21, 2013
Patients operated for hip fractures are older and have several conditions that have negative influences on the perioperative and postoperative prognosis.
Hip fractures can also be painful, which is stressful for the physiology of the patient. Many old patients have received to little fluid intake. They often have diuretic therapy, which even worsens dehydration/hypovolemia.
Some patients have to wait several days for surgery. Several studies have shown a high degree of complications and an increased mortality in this patient group.
Early preoperative optimization can improve the outcome. The available methods for optimization of the patient are complicated and time consuming.
The investigators wish with this study to try new approaches to find which patients still are dehydrated when they come to the operation ward.
The aim is to measure the color and density of the urine as well as to register the the variability in the plethysmographic curve before spinal anaesthesia.
These results will be compared to circulatory instability during and after surgery as well as to postoperative complications.
|Condition or disease||Intervention/treatment|
|Hip Fracture||Other: Urine density|
All patients with hip fractures planed fore surgery at the Hospital in Norrkoping will come into consideration to participate in study.
Many will however not be able to give consent. These will not be included in the study.
Directly preoperatively urine will be collected. Color and density will be measured/registered.
The pulseoximeter reading will be registered (Saturation, pulse, PI and PVI) before spinal anaesthesia and after spinal anaesthesia as well as during the surgery.
Two to three days postoperatively a follow up will be performed, to register complications (Circulatory instability, confusion, infection, affected kidney function/creatinine rise).
30 day postoperative mortality will also be controlled.
These results will be compared, to see if pulse oximeter readings or urine concentration can predict complications.
|Study Type :||Observational|
|Actual Enrollment :||45 participants|
|Official Title:||Indicators of Operative and Postoperative Complications in Patients Operated for Hip Fracture|
|Study Start Date :||January 2011|
|Actual Primary Completion Date :||July 2012|
|Actual Study Completion Date :||July 2012|
Patients operated for hip fracture, giving informed consent
Other: Urine density
measurement of urine color, density and plethysmographic variability index before and during surgery.
- mortality [ Time Frame: 30 days ]30-day mortality related to indices of dehydration (urine and pulse oximetry)
- operative and postoperative complications [ Time Frame: 3 days ]Number of complications according to a prospective list
Biospecimen Retention: None Retained
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01294930
|Anaesthesia dept, Vrinnevisjukhuset|
|Study Director:||Robert Hahn, MD PhD Prof||University Hospital, Linkoeping|