Lower Urinary Tract Dysfunction Database

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ClinicalTrials.gov Identifier: NCT01293110

Recruitment Status : Recruiting

First Posted : February 10, 2011

Last Update Posted : June 21, 2019

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Sponsor:

Information provided by (Responsible Party):

Thomas Kessler, Balgrist University Hospital

Study Description

Brief Summary:

Patients with neurological disease/injury often suffer from lower urinary tract symptoms, which frequently have a negative impact on the patients' health related quality of life. The prevalence of lower urinary tract dysfunction is high and the treatment is a challenge because available treatments may fail. In this study data of patients with lower urinary tract dysfunction treated at the University of Zürich, are prospectively and systematically collected in a database.

Condition or disease
Neurogenic Bladder Diseases of the Lower Urinary Tract: General Conditions

Detailed Description:

Lower urinary tract dysfunction is characterized by detrusor overactivity, detrusor sphincter dyssynergia, voiding dysfunction, stress incontinence, or a combination of these and frequently has a negative impact on the patients' health related quality of life. In addition, the treatment of lower urinary tract dysfunction is a challenge because conventional therapies may fail. Adequate treatment and long-term follow-up of lower urinary tract dysfunction is important to achieve/maintain continence and preserve renal function. Thus, we aim to prospectively collect clinical, video-urodynamic and radiological data of patients with neurogenic lower urinary tract dysfunction treated at the University of Zürich in a database.

Study Design

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Study Type :	Observational
Estimated Enrollment :	7000 participants
Observational Model:	Case-Only
Time Perspective:	Prospective
Official Title:	Database of Patients With Lower Urinary Tract Dysfunction Treated at the University of Zürich
Study Start Date :	January 2010
Estimated Primary Completion Date :	January 2030
Estimated Study Completion Date :	January 2030

Groups and Cohorts

Outcome Measures

Primary Outcome Measures :

Survival of the patients [ Time Frame: first visit to death ]

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:	18 Years to 90 Years (Adult, Older Adult)
Sexes Eligible for Study:	All
Accepts Healthy Volunteers:	Yes
Sampling Method:	Non-Probability Sample

Study Population

Ages Eligibility: minimum 18 years Genders Eligibility: female and male

Criteria

Inclusion Criteria:

patient of Balgrist University Hospital
patient of University Hospital Zürich
urodynamic examination
written informed consent

Exclusion Criteria:

no written informed consent

Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01293110

Contacts

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Contact: Thomas M Kessler, MD	+41 44 386 39 07	thomas.kessler@balgrist.ch
Contact: Jure Tornic	+41 44 386 39 07	jure.tornic@balgrist.ch

Locations

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Switzerland
Spinal Cord Injury Center & Research, University of Zürich, Balgrist University Hospital	Recruiting
Zürich, Switzerland, 8008
Contact: Thomas M Kessler, MD +41 44 386 39 07 thomas.kessler@balgrist.ch

Sponsors and Collaborators

University of Zurich

Investigators

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Principal Investigator:	Thomas M Kessler	Universitätsklinik Balgrist

More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

Walter M, Knupfer SC, Cragg JJ, Leitner L, Schneider MP, Mehnert U, Krassioukov AV, Schubert M, Curt A, Kessler TM. Prediction of autonomic dysreflexia during urodynamics: a prospective cohort study. BMC Med. 2018 Apr 13;16(1):53. doi: 10.1186/s12916-018-1040-8.

Leitner L, Guggenbuhl-Roy S, Knupfer SC, Walter M, Schneider MP, Tornic J, Sammer U, Mehnert U, Kessler TM. More Than 15 Years of Experience with Intradetrusor OnabotulinumtoxinA Injections for Treating Refractory Neurogenic Detrusor Overactivity: Lessons to Be Learned. Eur Urol. 2016 Sep;70(3):522-8. doi: 10.1016/j.eururo.2016.03.052. Epub 2016 Apr 19.

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Responsible Party:	Thomas Kessler, executive physician, Balgrist University Hospital
ClinicalTrials.gov Identifier:	NCT01293110
Other Study ID Numbers:	KEK-2010-0207/0/PB_2016-0189
First Posted:	February 10, 2011 Key Record Dates
Last Update Posted:	June 21, 2019
Last Verified:	June 2019
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD:	No

Keywords provided by Thomas Kessler, Balgrist University Hospital:


urodynamics neurogenic lower urinary tract dysfunction neurological disease/injury

Additional relevant MeSH terms:

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Urinary Bladder, Neurogenic Neurologic Manifestations Nervous System Diseases Urinary Bladder Diseases Urologic Diseases	Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Urogenital Diseases Male Urogenital Diseases

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