Skin Sterility After Ethyl-Chloride Spray
The aim of this study is to investigate sterility of ethyl-chloride topical anesthetic spray when used prior to an injection. The hypothesis is that the spray does not change the sterility of the injection site after skin is prepped.
Skin Sterility After Use of Ethyl-chloride Spray.
|Study Design:||Time Perspective: Prospective|
|Official Title:||Skin Sterility After Ethyl-Chloride Spray|
- culture positivity [ Time Frame: 5 days ] [ Designated as safety issue: No ]Cultures before and after Ethyl-Chloride spray are compared to see if there is any difference.
- Native skin flora [ Time Frame: 5days ] [ Designated as safety issue: No ]Cultures of skin prior to skin prep are taken to define to native flora at the shoulder and knee area.
|Study Start Date:||February 2009|
|Study Completion Date:||October 2010|
|Primary Completion Date:||October 2010 (Final data collection date for primary outcome measure)|
15 healthy volunteers were recruited
This is an IRB-approved, prospective, blinded, controlled study. In the first set of experiments, skin sterility is assessed. Healthy adult subjects are prepared for mock injections of shoulders and knees. No injection is performed. Each site has a set of 3 skin cultures: 1) prior to the alcohol prep (pre-prep), 2) post-alcohol prep (pre-spray), and 3) after ethyl-chloride was sprayed on the site (post-spray). In the second set of experiments, sterility of ethyl chloride is tested directly by culturing the liquid from the spray bottles.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01292850
|United States, New Jersey|
|Newark, New Jersey, United States, 07103|
|Principal Investigator:||Robin M Gehrmann, MD||Rutgers, The State University of New Jersey|